Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.51 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6691043 | 1.00 | CD274 (0.51) | CD274PDCD1MAOBPPARAPPARG | |
| SCHEMBL6693470 | 0.81 | LMNA (0.44) | CD274PDCD1MAOB | |
| SCHEMBL6688301 | 0.81 | PTPRZ1 (0.43) | CD274PDCD1PPARAPPARGPPARD | |
| SCHEMBL6688302 | 0.81 | PTPRZ1 (0.43) | CD274PDCD1PPARAPPARGPPARD | |
| SCHEMBL6686195 | 0.79 | MAOB (0.50) | CD274PDCD1MAOBPPARAFFAR1 | |
| SCHEMBL6686190 | 0.79 | MAOB (0.50) | CD274PDCD1MAOBPPARAFFAR1 | |
| SCHEMBL8935445 | 0.74 | BCHE (0.55) | — | |
| SCHEMBL3288931 | 0.74 | BCHE (0.55) | — | |
| SCHEMBL3291152 | 0.74 | BCHE (0.55) | — | |
| SCHEMBL6692071 | 0.73 | NPC1 (0.55) | CD274PDCD1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |