Ether

Ether

SCHEMBL6685897

CCOCC.Cc1cc(F)c(C)c(F)c1

nearest known ligand 0.38

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Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HPGD P15428 2/20 0.33
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.31
KAT6A Q92794 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30668 0.82 HDAC1 (0.48) HDAC1HDAC6TSHR
Ether SCHEMBL5474605 0.79 ALDH1A1 (0.42) HPGDTSHRSMN1; SMN2
Nitrogen SCHEMBL10699058 0.76 HDAC1 (0.44) HDAC1HDAC6TSHR
SCHEMBL12231919 0.71 GRIN2D (0.37) TSHRSMN1; SMN2KAT6A
SCHEMBL12700587 0.71 HDAC1 (0.38) HDAC1HDAC6HPGD
SCHEMBL15086896 0.71 NQO1 (0.46) TSHRSMN1; SMN2KAT6A
SCHEMBL1056730 0.69 RAPGEF4 (0.43) HDAC1HDAC6
SCHEMBL31633777 0.69 RAPGEF4 (0.43) HDAC1HDAC6
SCHEMBL10018717 0.68 HDAC1 (0.39) HDAC1HDAC6
Nitrogen SCHEMBL8111949 0.68 HDAC1 (0.39) HDAC1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1160267-B1 CATALYST FOR OXIDATIVE POLYMERIZATION OF FLUOROPHENOL, METHOD OF OXIDATIVE POLYMERIZATION OF FLUOROPHENOL, AND POLY(OXYFLUOROPHENYLENE) DERIVATIVE JAPAN SCIENCE & TECH CORP (JP) 2004-08-04 EP disclosed