Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.64 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.64 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16625771 | 0.97 | CLK4 (0.61) | CLK4ADRB2CYP2A6NPC1RAB9A | |
| SCHEMBL3157659 | 0.88 | RAB9A (0.64) | CLK4ADRB2CYP2A6NPC1RAB9A | |
| SCHEMBL29637613 | 0.88 | CLK4 (0.54) | CLK4ADRB2CYP2A6NPC1RAB9A | |
| SCHEMBL29637612 | 0.88 | CLK4 (0.54) | CLK4ADRB2CYP2A6NPC1RAB9A | |
| SCHEMBL29637614 | 0.88 | CLK4 (0.54) | CLK4ADRB2CYP2A6NPC1RAB9A | |
| SCHEMBL33833 | 0.87 | NPC1 (0.62) | CLK4ADRB2CYP2A6NPC1RAB9A | |
| SCHEMBL28062294 | 0.87 | NPC1 (0.62) | CLK4ADRB2CYP2A6NPC1RAB9A | |
| SCHEMBL2258014 | 0.86 | CLK4 (0.52) | CLK4ADRB2CYP2A6NPC1RAB9A | |
| SCHEMBL1000179 | 0.86 | NPC1 (0.59) | CLK4ADRB2CYP2A6NPC1RAB9A | |
| SCHEMBL13364856 | 0.86 | CYP19A1 (0.53) | CLK4ADRB2CYP2A6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186045-B1 | 1,4-DIPYRIMIDINYLBENZENE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING IT | Chisso Corporation (JP) | 1989-03-22 | — | — | EP | claimed |
| US-4640796-A | 1,4-dipyrimidinylbenzene derivative | CHISSO CORPORATION (JP) | 1987-02-03 | — | — | US | claimed |
| EP-0690052-B1 | Use of pyrimidine groups containing conjugated compounds as electroluminescence materials | COVION ORGANIC SEMICONDUCTORS (DE) | 2004-11-24 | — | — | EP | disclosed |
| US-5948551-A | Use of conjugated compounds containing pyrimidine groups as electroluminescence materials | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-09-07 | — | — | US | disclosed |
| EP-0690052-A2 | Use of pyrimidine groups containing conjugated compounds as electroluminescence materials | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-03 | — | — | EP | disclosed |
| EP-0186045-B1 | 1,4-DIPYRIMIDINYLBENZENE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING IT | Chisso Corporation (JP) | 1989-03-22 | — | — | EP | disclosed |
| US-4640796-A | 1,4-dipyrimidinylbenzene derivative | CHISSO CORPORATION (JP) | 1987-02-03 | — | — | US | disclosed |
| US-4640796-A | 1,4-dipyrimidinylbenzene derivative | CHISSO CORPORATION (JP) | 1987-02-03 | — | — | US | disclosed |
| US-4640796-A | 1,4-dipyrimidinylbenzene derivative | CHISSO CORPORATION (JP) | 1987-02-03 | — | — | US | disclosed |
| EP-0186045-A1 | 1,4-Dipyrimidinylbenzene derivative and liquid crystal composition containing it | Chisso Corporation (JP) | 1986-07-02 | — | — | EP | disclosed |
| EP-0186045-A1 | 1,4-Dipyrimidinylbenzene derivative and liquid crystal composition containing it | Chisso Corporation (JP) | 1986-07-02 | — | — | EP | disclosed |
| EP-0186045-A1 | 1,4-Dipyrimidinylbenzene derivative and liquid crystal composition containing it | Chisso Corporation (JP) | 1986-07-02 | — | — | EP | disclosed |