Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.43 |
| ▸ | ELANE | P08246 | 3/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12274352 | 0.91 | VCAM1 (0.50) | MAPK1VCAM1PTGS1PTGS2ELANE | |
| SCHEMBL26530223 | 0.84 | MAPK1 (0.50) | MAPK1VCAM1PTGS1PTGS2GABRA1 | |
| SCHEMBL2955209 | 0.84 | MAPK1 (0.50) | MAPK1VCAM1PTGS1PTGS2ELANE | |
| SCHEMBL2955824 | 0.84 | MAPK1 (0.50) | MAPK1VCAM1PTGS1PTGS2ELANE | |
| SCHEMBL2954189 | 0.83 | MAPK1 (0.57) | MAPK1VCAM1PTGS1PTGS2ELANE | |
| SCHEMBL4309371 | 0.81 | APP (0.39) | CRHBPCRHR2ALDH1A1LMNAMAPT | |
| SCHEMBL27822367 | 0.79 | MAPK1 (0.61) | MAPK1VCAM1PTGS1PTGS2GABRA1 | |
| SCHEMBL21240 | 0.79 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPTTDP1L3MBTL1 | |
| SCHEMBL8679862 | 0.78 | PTGS1 (0.63) | MAPK1VCAM1PTGS1PTGS2ELANE | |
| SCHEMBL3365438 | 0.77 | MAPK1 (0.58) | MAPK1VCAM1PTGS1PTGS2ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074300-A2 | NOVEL PHOTOLABILE PROTECTIVE GROUPS FOR IMPROVED PROCESSES TO PREPARE OLIGONUCLEOTIDE ARRAYS | NIGU CHEMIE GMBH (DE) | 2004-09-02 | — | — | WO | disclosed |