Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2321634 | 0.90 | TSHR (0.57) | NPC1RAB9ATP53TSHRHDAC8 | |
| SCHEMBL901207 | 0.90 | TSHR (0.57) | NPC1RAB9ATP53TSHRHDAC8 | |
| SCHEMBL901209 | 0.90 | TSHR (0.57) | NPC1RAB9ATP53TSHRHDAC8 | |
| Hydrochloric Acid SCHEMBL4290507 | 0.88 | TSHR (0.55) | NPC1RAB9ATP53TSHRHDAC8 | |
| Terephthalic Acid SCHEMBL6654100 | 0.88 | TSHR (0.60) | NPC1RAB9AAKR1C3AKR1C1TP53 | |
| SCHEMBL24087489 | 0.84 | HDAC8 (0.56) | NPC1RAB9ATP53TSHRHDAC8 | |
| SCHEMBL8536046 | 0.82 | NPC1 (0.68) | NPC1RAB9AAKR1C3AKR1C1CYP2C9 | |
| SCHEMBL28005910 | 0.82 | ESR2 (0.59) | NPC1RAB9ATP53TSHRHDAC8 | |
| SCHEMBL8999823 | 0.82 | NPC1 (0.68) | NPC1RAB9AAKR1C3AKR1C1CYP2C9 | |
| SCHEMBL664284 | 0.82 | NPC1 (0.79) | NPC1RAB9AAKR1C3AKR1C1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0856025-B1 | CHOLESTERIC PHASE-FORMING POLYMERS AND THEIR USE | CELANESE VENTURES GMBH (DE) | 2003-01-15 | — | — | EP | claimed |
| CN-103664581-B | A kind of anti-, trans-4, the preparation method of 4 '-dicyclohexyl dioctyl phthalate | 中节能万润股份有限公司 | 2016-07-06 | — | — | CN | disclosed |
| US-20150080546-A1 | Production and Use of 3,4' and 4,4'-Dimethylbiphenyl Isomers | EXXONMOBIL CHEMICAL PATENTS INC. | 2015-03-19 | — | — | US | disclosed |
| EP-2808325-A1 | Substituted azoles, anti-viral active ingredient, pharmaceutical composition, method for the production and use thereof | Alla Chem, LLC. (US) | 2014-12-03 | — | — | EP | disclosed |
| CN-103664581-A | Preparation method of trans,trans-4,4'-dicyclohexyl phthalate | YANTAI VALIANT FINE CHEMICALS CO LTD | 2014-03-26 | — | — | CN | disclosed |
| EP-2657231-A2 | SUBSTITUTED AZOLES, ANTI-VIRAL ACTIVE INGREDIENT, PHARMACEUTICAL COMPOSITION, METHOD FOR THE PRODUCTION AND USE THEREOF | Ivachtchenko, Alexandre Vasilievich (US) | 2013-10-30 | — | — | EP | disclosed |
| US-20130253008-A1 | SUBSTITUTED AZOLES, ANTIVIRAL ACTIVE COMPONENT, PHARMACEUTICAL COMPOSITION, METHOD FOR PREPARATION AND USE THEREOF | ALLA CHEM LLC (US) | 2013-09-26 | — | — | US | disclosed |
| US-20130253008-A1 | SUBSTITUTED AZOLES, ANTIVIRAL ACTIVE COMPONENT, PHARMACEUTICAL COMPOSITION, METHOD FOR PREPARATION AND USE THEREOF | ALLA CHEM LLC (US) | 2013-09-26 | — | — | US | disclosed |
| WO-2012074437-A2 | SUBSTITUTED AZOLES, ANTI-VIRAL ACTIVE INGREDIENT, PHARMACEUTICAL COMPOSITION, METHOD FOR THE PRODUCTION AND USE THEREOF | АЛЛА ХЕМ, ЛЛС (US) | 2012-06-07 | — | — | WO | disclosed |
| US-20110250509-A1 | SECONDARY BATTERY AND ELECTRONIC DEVICE | SONY CORPORATION (JP) | 2011-10-13 | — | — | US | disclosed |
| CN-100442092-C | Optical film and liquid crystal display element | NIPPON OIL CORP (JP) | 2008-12-10 | — | — | CN | disclosed |
| CN-100442092-C | Optical film and liquid crystal display element | NIPPON OIL CORP (JP) | 2008-12-10 | — | — | CN | disclosed |
| CN-1759334-A | Optical film and liquid crystal display element | NIPPON OIL CORP (JP) | 2006-04-12 | — | — | CN | disclosed |
| CN-1759334-A | Optical film and liquid crystal display element | NIPPON OIL CORP (JP) | 2006-04-12 | — | — | CN | disclosed |
| JP-2004272110-A | OPTICAL FILM AND LIQUID CRYSTAL DISPLAY ELEMENT | NIPPON OIL CORP | 2004-09-30 | — | — | JP | disclosed |
| WO-2004081623-A1 | OPTICAL FILM AND LIQUID CRYSTAL DISPLAY DEVICE | NIPPON OIL CORPORATION (JP) | 2004-09-23 | — | — | WO | disclosed |
| EP-0856025-B1 | CHOLESTERIC PHASE-FORMING POLYMERS AND THEIR USE | CELANESE VENTURES GMBH (DE) | 2003-01-15 | — | — | EP | disclosed |
| US-6107447-A | LIQUID CRYSTALLINE POLYMERS | HOECHST RESEARCH TECHNOLOGY DEUTCHLAND GMBH & CO. KG (DE) | 2000-08-22 | — | — | US | disclosed |
| EP-0856025-A1 | CHOLESTERIC PHASE-FORMING POLYMERS, PROCESS FOR THEIR PREPARATION AND THEIR USE | Hoechst Research & Technology Deutschland GmbH & Co. KG (DE) | 1998-08-05 | — | — | EP | disclosed |
| WO-1997014739-A1 | CHOLESTERIC PHASE-FORMING POLYMERS, PROCESS FOR THEIR PREPARATION AND THEIR USE | HOECHST RESEARCH & TECHNOLOGY (DE) | 1997-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150080546-A1 | Production and Use of 3,4' and 4,4'-Dimethylbiphenyl Isomers | CYP4B1, HPD, DDT | NPC1 4871/4885RAB9A 4370/4885AKR1C3 187/4885 |
| US-20130253008-A1 | SUBSTITUTED AZOLES, ANTIVIRAL ACTIVE COMPONENT, PHARMACEUTICAL COMPOSITION, METHOD FOR PREPARATION AND USE THEREOF | HCCS, EIF2AK2, HAVCR2 | NPC1 1122/4885RAB9A 4117/4885AKR1C3 101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.