Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.40 |
| ▸ | HTR3B | O95264 | 2/20 | 0.40 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686250 | 1.00 | NPC1 (0.46) | NPC1RAB9AMEN1KMT2AHSP90AA1 | |
| SCHEMBL3432776 | 0.78 | ALDH1A1 (0.44) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3432777 | 0.78 | ALDH1A1 (0.44) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9819772 | 0.77 | NPC1 (0.43) | NPC1RAB9AMEN1KMT2AHSP90AA1 | |
| SCHEMBL10431203 | 0.77 | ALDH1A1 (0.42) | MEN1KMT2ASMN1; SMN2KCNA3TDP1 | |
| SCHEMBL10431202 | 0.77 | ALDH1A1 (0.42) | MEN1KMT2ASMN1; SMN2KCNA3TDP1 | |
| SCHEMBL3195894 | 0.77 | ALDH1A1 (0.42) | MEN1KMT2ASMN1; SMN2KCNA3TDP1 | |
| SCHEMBL9056068 | 0.77 | KCNH2 (0.30) | — | |
| SCHEMBL3260618 | 0.74 | MEN1 (0.41) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL3260614 | 0.74 | MEN1 (0.41) | NPC1RAB9AMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200050-B1 | DYEING AGENT FOR KERATINOUS FIBRES | HENKEL KGAA (DE) | 2004-09-22 | — | — | EP | disclosed |
| US-6755872-B1 | ALDEHYDE OR KETONE AND NITROAMINE HETEROAROMATICS; NO OXIDING AGENT REQUIRED; COLORFASTNESS; GREY COVERAGE; COLOR DEPTH | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-06-29 | — | — | US | disclosed |
| EP-1200050-A2 | DYEING AGENT FOR KERATINOUS FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001010379-A3 | DYEING AGENT FOR KERATINOUS FIBRES | HENKEL KGAA (DE) | 2001-11-15 | — | — | WO | disclosed |
| WO-2001010379-A2 | DYEING AGENT FOR KERATINOUS FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-02-15 | — | — | WO | disclosed |