Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 11/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687640 | 0.85 | MALT1 (0.58) | MALT1PTGS2PTGS1L3MBTL1 | |
| SCHEMBL6687179 | 0.84 | PTGS2 (0.71) | MALT1PTGS2PTGS1L3MBTL1 | |
| SCHEMBL6682126 | 0.84 | MALT1 (0.53) | MALT1PTGS2PTGS1L3MBTL1MTNR1A | |
| SCHEMBL6687464 | 0.83 | MALT1 (0.51) | MALT1PTGS2PTGS1L3MBTL1MTNR1A | |
| SCHEMBL5150845 | 0.83 | PTGS2 (0.43) | MALT1PTGS2PTGS1MTNR1AMTNR1B | |
| SCHEMBL6687282 | 0.80 | PTGS2 (0.53) | MALT1PTGS2PTGS1L3MBTL1MTNR1A | |
| SCHEMBL5148721 | 0.77 | PTGS2 (0.60) | MALT1PTGS2PTGS1 | |
| SCHEMBL5150568 | 0.76 | CCKAR (0.46) | MALT1PTGS2PTGS1MTNR1AMTNR1B | |
| SCHEMBL6681832 | 0.76 | PTGS1 (0.57) | MALT1PTGS2PTGS1L3MBTL1 | |
| SCHEMBL5152241 | 0.75 | PTGS1 (0.49) | MALT1PTGS2PTGS1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060367-A1 | IMIDAZOLE AND TRIAZOLE DERIVATIVES USEFUL AS SELECTIVE COX-1 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-22 | — | — | WO | claimed |