Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MYOF | Q9NZM1 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687455 | 0.90 | PTGS2 (0.42) | PTGS2PTGS1L3MBTL1MALT1CYP3A4 | |
| SCHEMBL6687179 | 0.89 | PTGS2 (0.71) | PTGS2PTGS1L3MBTL1MALT1CYP3A4 | |
| SCHEMBL6681028 | 0.87 | PTGS2 (0.53) | PTGS2PTGS1L3MBTL1MALT1 | |
| SCHEMBL6682106 | 0.84 | PTGS2 (0.60) | PTGS2PTGS1L3MBTL1MALT1CYP3A4 | |
| Hydrochloric Acid SCHEMBL6687629 | 0.83 | PTGS2 (0.58) | PTGS2PTGS1L3MBTL1MALT1CYP3A4 | |
| SCHEMBL6682132 | 0.83 | PTGS2 (0.53) | PTGS2PTGS1L3MBTL1MALT1 | |
| SCHEMBL5148697 | 0.81 | PTGS2 (0.46) | PTGS2PTGS1L3MBTL1MALT1MTNR1A | |
| SCHEMBL6132473 | 0.80 | PTGS2 (0.67) | PTGS2PTGS1L3MBTL1CYP3A4CYP2C9 | |
| SCHEMBL6686281 | 0.80 | MALT1 (0.54) | PTGS2PTGS1L3MBTL1MALT1MTNR1A | |
| SCHEMBL5147861 | 0.80 | PTGS2 (0.65) | PTGS2PTGS1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060367-A1 | IMIDAZOLE AND TRIAZOLE DERIVATIVES USEFUL AS SELECTIVE COX-1 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-22 | — | — | WO | disclosed |