SCHEMBL6686359

SCHEMBL6686359

CCCCCCCCOC(C)OCCCCCCCC

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.54
THRB P10828 2/20 0.44
TSHR P16473 1/20 0.44
LMNA P02545 1/20 0.43
GBA1 P04062 1/20 0.43
MEN1 O00255 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
MAPT P10636 1/20 0.41
LPAR1 Q92633 4/20 0.40
LPAR3 Q9UBY5 4/20 0.40
LPAR2 Q9HBW0 1/20 0.40
USP2 O75604 1/20 0.40
SPHK1 Q9NYA1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16841236 1.00 DNM1 (0.54) DNM1THRBTSHRLMNAGBA1
SCHEMBL25509452 1.00 DNM1 (0.54) DNM1THRBTSHRLMNAGBA1
SCHEMBL873400 1.00 DNM1 (0.54) DNM1THRBTSHRLMNAGBA1
SCHEMBL28557811 0.97 DNM1 (0.50) DNM1THRBTSHRLMNAGBA1
SCHEMBL25505152 0.95 DNM1 (0.50) DNM1THRBTSHRLMNAGBA1
SCHEMBL27859745 0.94 DNM1 (0.48) DNM1THRBTSHRLMNAGBA1
SCHEMBL17936343 0.93 LMNA (0.57) DNM1THRBTSHRLMNAGBA1
SCHEMBL873415 0.93 LMNA (0.57) DNM1THRBTSHRLMNAGBA1
SCHEMBL11044298 0.93 LMNA (0.57) DNM1THRBTSHRLMNAGBA1
SCHEMBL28167608 0.92 DNM1 (0.46) DNM1THRBTSHRLMNAGBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023114937-A2 FLUORINATED CATIONIC LIPIDS FOR USE IN LIPID NANOPARTICLES Acuitas Therapeutics, Inc. (CA) 2023-06-22 WO disclosed
WO-2023114944-A1 FLUORINATED CATIONIC LIPIDS FOR USE IN LIPID NANOPARTICLES Acuitas Therapeutics, Inc. (CA) 2023-06-22 WO disclosed
EP-1099983-B1 Chemically amplified positive resist composition and patterning method SHINETSU CHEMICAL CO (JP) 2014-08-06 EP disclosed
EP-0855436-B1 Use of acetals and triglycerides as Ecodiesel CELANESE CHEM EUROPE GMBH (DE) 2004-09-22 EP disclosed
EP-0512501-B1 Use of acetals CLARIANT GMBH (DE) 2001-11-28 EP disclosed
EP-0855436-A2 Ecodiesel Clariant GmbH (DE) 1998-07-29 EP disclosed
US-5759963-A LESS TOXIC, WATER IMMISCIBLE EMULSION DRILLING MUD SHOWING GOOD BIODEGRADABILITY HOECHST AKTIENGESELLSCHAFT (DE) 1998-06-02 US disclosed
EP-0512501-A2 Use of acetals HOECHST AKTIENGESELLSCHAFT (DE) 1992-11-11 EP disclosed