Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6699653 | 0.87 | MEN1 (0.41) | MEN1KMT2AMAPTF2LMNA | |
| SCHEMBL6681896 | 0.85 | MEN1 (0.41) | MEN1KMT2AMAPTF2LMNA | |
| SCHEMBL6699650 | 0.85 | MEN1 (0.42) | MEN1KMT2AMAPTF2LMNA | |
| SCHEMBL6703108 | 0.82 | MEN1 (0.45) | MEN1KMT2AMAPTF2LMNA | |
| SCHEMBL6701229 | 0.77 | MAPT (0.48) | MEN1KMT2AMAPTF2LMNA | |
| SCHEMBL6684918 | 0.77 | NR3C1 (0.38) | — | |
| SCHEMBL6693517 | 0.75 | MEN1 (0.42) | MEN1KMT2AMAPTF2LMNA | |
| SCHEMBL6701221 | 0.75 | MAPT (0.49) | MEN1KMT2AMAPTF2LMNA | |
| SCHEMBL7847389 | 0.74 | MEN1 (0.49) | MEN1KMT2AMAPTF2LMNA | |
| SCHEMBL6697945 | 0.73 | MEN1 (0.43) | MEN1KMT2AMAPTF2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |