Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | F13A1 | P00488 | 3/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14430375 | 0.89 | FFAR1 (0.54) | FFAR4FFAR1MRGPRX4HDAC6POLB | |
| SCHEMBL31584797 | 0.87 | FFAR1 (0.52) | FFAR4FFAR1F13A1ACLY | |
| SCHEMBL8240809 | 0.84 | PSEN1 (0.47) | FFAR4FFAR1F13A1PSEN1PSEN2 | |
| SCHEMBL4778926 | 0.82 | ACLY (0.58) | FFAR4FFAR1ACLY | |
| SCHEMBL26679325 | 0.81 | SMN1; SMN2 (0.50) | F13A1MRGPRX4ACLYHDAC3MAPK1 | |
| SCHEMBL18780574 | 0.81 | F13A1 (0.51) | F13A1ACLYPOLB | |
| SCHEMBL12713147 | 0.81 | F13A1 (0.43) | FFAR1F13A1ACLYHDAC3MAPK1 | |
| SCHEMBL341990 | 0.81 | NPSR1 (0.50) | FFAR1F13A1MRGPRX4SMN1; SMN2POLB | |
| SCHEMBL19584858 | 0.81 | NPC1 (0.45) | FFAR4FFAR1F13A1HDAC3MAPK1 | |
| SCHEMBL28629620 | 0.81 | F13A1 (0.43) | FFAR4FFAR1F13A1HDAC3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071389-A2 | NON-STEROIDAL INFALMMATION INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-08-26 | — | — | WO | disclosed |