Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2393802 | 0.89 | POLB (0.39) | ALDH1A1MAPTAKR1B1GPR35HTT | |
| SCHEMBL5108192 | 0.87 | ALDH1A1 (0.41) | ALDH1A1MAPTGPR35HTTPDE4A | |
| SCHEMBL21050043 | 0.85 | KCNK2 (0.37) | ALDH1A1MAPTAKR1B1HTTTP53 | |
| SCHEMBL12584980 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MAPTGPR35HTTPDE4A | |
| SCHEMBL13735316 | 0.81 | ALDH1A1 (0.37) | ALDH1A1MAPTGPR35HTTPDE4A | |
| SCHEMBL7053647 | 0.79 | PKM (0.51) | ALDH1A1MAPTAKR1B1GPR35HTT | |
| SCHEMBL20298763 | 0.76 | NPC1 (0.43) | ALDH1A1MAPTAKR1B1MAPK1MITF | |
| SCHEMBL1811629 | 0.76 | PTGS1 (0.41) | ALDH1A1SORT1SMN1; SMN2HSD11B1 | |
| SCHEMBL29057016 | 0.75 | AKR1B1 (0.50) | ALDH1A1MAPTAKR1B1GPR35HTT | |
| SCHEMBL6268161 | 0.74 | PDE4A (0.39) | ALDH1A1MAPTGPR35HTTPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |