Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RGS12 | O14924 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687177 | 0.82 | GAA (0.35) | CXCR2KDM4ELMNAGAAMAPT | |
| SCHEMBL3391681 | 0.73 | ALDH1A1 (0.36) | KDM4ERGS12LMNAPOLBGAA | |
| SCHEMBL3393400 | 0.66 | ALDH1A1 (0.44) | CA2KDM4ELMNAGAAMAPT | |
| SCHEMBL390919 | 0.64 | ALDH1A1 (0.65) | CA2LMNAPOLBMAPTALDH1A1 | |
| SCHEMBL3389367 | 0.64 | ALDH1A1 (0.45) | CA2KDM4ELMNAMAPTHPGD | |
| SCHEMBL3390541 | 0.63 | ALDH1A1 (0.42) | CXCR2CA2KDM4ELMNAPOLB | |
| SCHEMBL6690666 | 0.63 | ALDH1A1 (0.42) | CA2KDM4ELMNAPOLBGAA | |
| SCHEMBL3391703 | 0.62 | KDM4E (0.31) | KDM4ERGS12LMNAPOLBGAA | |
| SCHEMBL8761359 | 0.61 | ALDH1A1 (0.45) | CA2LMNAPOLBMAPTTSHR | |
| SCHEMBL8815527 | 0.61 | ALDH1A1 (0.42) | KDM4ELMNAGAAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004052313-A2 | ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-06-24 | — | — | WO | disclosed |