SCHEMBL3390541

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3390545	0.87	LMNA (0.38)	ALDH1A1POLBMAPK1HSD17B10KDM4E
	SCHEMBL6690666	0.80	ALDH1A1 (0.42)	ALDH1A1POLBMAPK1HSD17B10KDM4E
	SCHEMBL1522527	0.77	HSD17B10 (0.37)	ALDH1A1POLBMAPK1HSD17B10KDM4E
	SCHEMBL8286607	0.76	CA12 (0.53)	ALDH1A1POLBMAPK1HSD17B10KDM4E
	SCHEMBL6687177	0.75	GAA (0.35)	ALDH1A1HSD17B10KDM4EHPGDCXCR2
	SCHEMBL390919	0.74	ALDH1A1 (0.65)	ALDH1A1POLBMAPK1CA12CA1
	SCHEMBL3392351	0.72	MAPT (0.46)	ALDH1A1POLBHSD17B10KDM4ECA12
	SCHEMBL3393400	0.67	ALDH1A1 (0.44)	ALDH1A1KDM4ECA12CA1CA2
	SCHEMBL4649502	0.66	CXCR2 (0.69)	CXCR2
	SCHEMBL8683168	0.65	CA12 (0.55)	ALDH1A1POLBMAPK1HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.