Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17798406 | 0.84 | PIM1 (0.49) | NR4A2PIM1PIM3MAPTL3MBTL1 | |
| SCHEMBL6691799 | 0.81 | AHR (0.56) | AHRNR4A2PIM1MAPTL3MBTL1 | |
| SCHEMBL10201987 | 0.81 | AHR (0.56) | AHRPIM1MAPTL3MBTL1NPC1 | |
| SCHEMBL31175276 | 0.81 | AHR (0.56) | AHRNR4A2PIM1MAPTL3MBTL1 | |
| SCHEMBL9485757 | 0.77 | MPL (0.61) | NR4A2PIM1PIM3MAPTMAPK1 | |
| SCHEMBL17798493 | 0.76 | PIM1 (0.42) | NR4A2PIM1PIM3MAPTL3MBTL1 | |
| SCHEMBL6625709 | 0.75 | NR4A2 (0.56) | NR4A2PIM1PIM3MAPTNPC1 | |
| SCHEMBL3511612 | 0.74 | LMNA (0.59) | NR4A2MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL70429 | 0.74 | LMNA (0.59) | NR4A2MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL17798752 | 0.74 | NR4A2 (0.68) | NR4A2PIM1PIM3MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004063156-A1 | NOVEL INDOLE DERIVATES AS FABP-4 INHIBITORS | BIOVITRUM AB (SE) | 2004-07-29 | — | — | WO | claimed |
| WO-2004063156-A1 | NOVEL INDOLE DERIVATES AS FABP-4 INHIBITORS | BIOVITRUM AB (SE) | 2004-07-29 | — | — | WO | disclosed |