SCHEMBL70429

SCHEMBL70429

COC(=O)c1cccc2c(C(=O)OC)cccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.59
TSHR P16473 1/20 0.59
ALDH1A1 P00352 2/20 0.57
CFTR P13569 1/20 0.57
HSD17B10 Q99714 1/20 0.57
KDM4E B2RXH2 3/20 0.55
POLB P06746 1/20 0.55
ATM Q13315 1/20 0.55
BRD4 O60885 2/20 0.55
NR4A2 P43354 4/20 0.53
CREBBP Q92793 1/20 0.53
PSMD14 O00487 1/20 0.53
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA9 Q16790 2/20 0.52
CA12 O43570 1/20 0.52
CA7 P43166 1/20 0.52
CA14 Q9ULX7 1/20 0.52
MAPT P10636 2/20 0.50
KMT2A Q03164 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3230050 0.92 NR4A2 (0.53) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL29434198 0.91 BRD4 (0.59) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL70381 0.91 BRD4 (0.59) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL29197395 0.90 LMNA (0.50) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL9300933 0.90 LMNA (0.66) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL23909597 0.90 ALDH1A1 (0.53) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL12345028 0.90 LMNA (0.50) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL3207564 0.90 NR4A2 (0.58) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL23909537 0.90 LMNA (0.50) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL2646933 0.88 KMT2A (0.57) LMNATSHRALDH1A1CFTRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230257624-A1 AMORPHOUS COPOLYESTER RESIN FOR INDUSTRIAL COATINGS AND METHODS FOR COATING A METAL SURFACE USING SUCH COATING COMPOSITIONS BOSTIK, INC. 2023-08-17 US claimed
EP-4179002-A1 AMORPHOUS COPOLYESTER RESIN FOR INDUSTRIAL COATINGS AND METHODS FOR COATING A METAL SURFACE USING SUCH COATING COMPOSITIONS Bostik, Inc. (US) 2023-05-17 EP claimed
CN-115777000-A Amorphous copolyester resins for industrial coatings and method for coating metal surfaces using such coating compositions 波士胶公司 2023-03-10 CN claimed
WO-2022010963-A1 AMORPHOUS COPOLYESTER RESIN FOR INDUSTRIAL COATINGS AND METHODS FOR COATING A METAL SURFACE USING SUCH COATING COMPOSITIONS BOSTIK, INC. (US) 2022-01-13 WO claimed
CN-106800643-A A kind of preparation method of high-fire resistance isobide type atactic polyester 中国科学院化学研究所 2017-06-06 CN claimed
US-8859690-B2 Biodegradable composite, the preparation process thereof, and a disposable article made therefrom CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2014-10-14 US claimed
US-20120329924-A1 Biodegradable Composite, The Preparation Process Thereof, And A Disposable Article Made Therefrom BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2012-12-27 US claimed
US-6252037-B1 POLYESTERETHER COPOLYMER UNICHEMA CHEMIE B.V. (NL) 2001-06-26 US claimed
EP-0441347-B1 Method of producing naphthalene dicarboxylic acid KAWASAKI STEEL CO (JP) 1994-08-31 EP claimed
US-5274185-A Reacting a dialkyl ester of naphthalene dicarbosylic acid in a solvent including a monocarboxylic acid KAWASAKI STEEL CORPORATION (JP) 1993-12-28 US claimed
EP-0441347-A1 Method of producing naphthalene dicarboxylic acid KAWASAKI STEEL CORPORATION (JP) 1991-08-14 EP claimed
EP-3860636-B1 MATRIPTASE 2 INHIBITORS AND USES THEREOF DISC MEDICINE INC (US) 2026-01-28 EP disclosed
US-12428415-B2 Matriptase 2 inhibitors and uses thereof DISC MEDICINE, INC. (US) 2025-09-30 US disclosed
CN-119790104-A Thermoplastic resin composition and molded article produced therefrom 乐天化学株式会社 2025-04-08 CN disclosed
CN-115505114-B Solvent-free polysiloxane modified polyester resin, and preparation method and application thereof 长兴化学工业(中国)有限公司 2024-03-08 CN disclosed
US-4739103-A CHEMICAL RESISTANT, CROSSLINKING AGENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-04-19 US disclosed
EP-0190847-A2 Perfluorocycloalkane carbonyl fluorides and their derivatives MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-08-13 EP disclosed
US-4062972-A Polychlorinated naphthalenic pesticides MARATHON OIL COMPANY (US) 1977-12-13 US disclosed
US-4022827-A Heptachloro-alpha-naphthoyl chloride MARATHON OIL COMPANY (US) 1977-05-10 US disclosed
US-3939198-A Chlorinated naphthalene esters MARATHON OIL COMPANY (US) 1976-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12428415-B2 Matriptase 2 inhibitors and uses thereof MMP7, MATR3, SPINT2 LMNA 1207/4885TSHR 4421/4885ALDH1A1 3877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.