Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22135588 | 0.84 | KDM4E (0.64) | KDM4ETP53ALOX15ALDH1A1MEN1 | |
| SCHEMBL11223887 | 0.83 | MAPT (0.55) | KDM4ETP53ALDH1A1KMT2AHPGD | |
| SCHEMBL3434867 | 0.81 | KDM4E (0.50) | KDM4ETP53ALOX15ALDH1A1MEN1 | |
| SCHEMBL8347835 | 0.80 | KDM4E (0.59) | KDM4ETP53ALOX15ALDH1A1MEN1 | |
| SCHEMBL96583 | 0.79 | MAPT (0.54) | KDM4ETP53ALDH1A1KMT2AHPGD | |
| SCHEMBL25261375 | 0.78 | KDM4E (0.61) | KDM4ETP53ALOX15ALDH1A1MEN1 | |
| SCHEMBL8234481 | 0.78 | KDM4E (0.56) | KDM4ETP53ALOX15ALDH1A1MEN1 | |
| SCHEMBL22557984 | 0.77 | KDM4E (0.57) | KDM4ETP53ALOX15ALDH1A1MEN1 | |
| SCHEMBL14015785 | 0.77 | KDM4E (0.56) | KDM4ETP53ALOX15ALDH1A1MEN1 | |
| Bicarbonate SCHEMBL5074471 | 0.76 | KDM4E (0.63) | KDM4ETP53ALOX15ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040186151-A1 | Substituted azole derivatives as therapeutic agents | TRANSTECH PHARMA, INC. | 2004-09-23 | — | — | US | claimed |
| WO-2004071448-A2 | SUBSTITUTED AZOLE DERIVATIVES AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | TRANSTECH PHARMA INC. (US) | 2004-08-26 | — | — | WO | claimed |
| EP-3956294-A1 | CONJUGATES OF AUXIN ANALOGS | The State of Israel, Ministry of Agriculture and Rural Development, Agricultural Research Organization (ARO) (Volcani Center) (IL) | 2022-02-23 | — | — | EP | disclosed |
| US-20220030866-A1 | CONJUGATES OF AUXIN ANALOGS | THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (IL) | 2022-02-03 | — | — | US | disclosed |
| WO-2020212993-A1 | CONJUGATES OF AUXIN ANALOGS | THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) | 2020-10-22 | — | — | WO | disclosed |
| US-20040186151-A1 | Substituted azole derivatives as therapeutic agents | TRANSTECH PHARMA, INC. | 2004-09-23 | — | — | US | disclosed |
| WO-2004071448-A2 | SUBSTITUTED AZOLE DERIVATIVES AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | TRANSTECH PHARMA INC. (US) | 2004-08-26 | — | — | WO | disclosed |
| US-4349488-A | Process for producing esters of 3,5-dibromo-4-hydroxybenzonitrile | GREAT LAKES CHEMICAL CORPORATION (US) | 1982-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220030866-A1 | CONJUGATES OF AUXIN ANALOGS | CROCC, CCNY, AGXT | KDM4E 3338/4885TP53 4033/4885ALOX15 2518/4885 |
| US-20040186151-A1 | Substituted azole derivatives as therapeutic agents | PTPRS, PTPRO, PTPRJ | KDM4E 672/4885TP53 1088/4885ALOX15 2189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.