Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SCN4A | P35499 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11031302 | 0.82 | MEN1 (0.48) | KDM4ECYP1A2CYP2C9HIF1ATP53 | |
| SCHEMBL5255078 | 0.81 | L3MBTL1 (0.45) | KDM4ETP53ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2641277 | 0.81 | TDP1 (0.56) | SMN1; SMN2HPGDTSHRGAAHTT | |
| SCHEMBL6686754 | 0.81 | KDM4E (0.57) | KDM4ECYP1A2CYP2C9HIF1ATP53 | |
| SCHEMBL11704067 | 0.79 | FFAR4 (0.37) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL5541035 | 0.79 | MRGPRX4 (0.47) | HPGDTSHRMRGPRX4KCNH2 | |
| SCHEMBL27565960 | 0.79 | NPC1 (0.48) | KDM4ECYP1A2CYP2C9ALDH1A1LMNA | |
| SCHEMBL11331289 | 0.78 | ALDH1A1 (0.45) | KDM4ECYP1A2CYP2C9ALDH1A1LMNA | |
| SCHEMBL8405377 | 0.78 | LMNA (0.50) | KDM4ECYP1A2CYP2C9HIF1ATP53 | |
| SCHEMBL22135588 | 0.77 | KDM4E (0.64) | KDM4ECYP1A2CYP2C9HIF1ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112745269-A | Phenyl isoxazoline compound and application thereof | 沈阳中化农药化工研发有限公司 | 2021-05-04 | — | — | CN | claimed |
| WO-2024129931-A1 | ALPHA-V BETA-6(ανβ6) INTEGRIN LIGANDS FOR EXTRAHEPATIC DELIVERY | ALNYLAM PHARMACEUTICALS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| CN-112745269-B | Phenyl isoxazoline compound and application thereof | 沈阳中化农药化工研发有限公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-114206831-A | Conjugates of auxin analogs | 以色列国家农业部、农村发展农业研究组织·沃尔卡尼中心 | 2022-03-18 | — | — | CN | disclosed |
| EP-3956294-A1 | CONJUGATES OF AUXIN ANALOGS | The State of Israel, Ministry of Agriculture and Rural Development, Agricultural Research Organization (ARO) (Volcani Center) (IL) | 2022-02-23 | — | — | EP | disclosed |
| US-20220030866-A1 | CONJUGATES OF AUXIN ANALOGS | THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (IL) | 2022-02-03 | — | — | US | disclosed |
| CN-112745269-A | Phenyl isoxazoline compound and application thereof | 沈阳中化农药化工研发有限公司 | 2021-05-04 | — | — | CN | disclosed |
| WO-2020212993-A1 | CONJUGATES OF AUXIN ANALOGS | THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) | 2020-10-22 | — | — | WO | disclosed |
| CN-105753853-B | Isoxazoline-containing uracil compound and application thereof | 沈阳中化农药化工研发有限公司 | 2020-08-04 | — | — | CN | disclosed |
| CN-106536517-B | Isoxazoline-containing uracil compound and application thereof | 沈阳中化农药化工研发有限公司 | 2020-03-17 | — | — | CN | disclosed |
| US-10550111-B2 | Pyrimidine urea compound containing isoxazolines and use thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2020-02-04 | — | — | US | disclosed |
| EP-2247571-A2 | DERIVATIVES OF AMINOALKANOLS, METHOD OF OBTAINING OF AMINOALKANOLS AND THEIR USE | Uniwersytet Jagiellonski (PL) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009093916-A2 | DERIVATIVES OF AMINOALKANOLS, METHOD OF OBTAINING AMINOALKANOLS AND THEIR USE | UNIWERSYTET JAGIELLONSKI (PL) | 2009-07-30 | — | — | WO | disclosed |
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |
| US-4349488-A | Process for producing esters of 3,5-dibromo-4-hydroxybenzonitrile | GREAT LAKES CHEMICAL CORPORATION (US) | 1982-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10550111-B2 | Pyrimidine urea compound containing isoxazolines and use thereof | DDX6, OAT, DHX36 | KDM4E 1077/4885CYP1A2 230/4885CYP2C9 461/4885 |
| US-20220030866-A1 | CONJUGATES OF AUXIN ANALOGS | CROCC, CCNY, AGXT | KDM4E 3338/4885CYP1A2 858/4885CYP2C9 1886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.