Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 17/20 | 0.60 |
| ▸ | MMP3 | P08254 | 5/20 | 0.60 |
| ▸ | MMP2 | P08253 | 5/20 | 0.58 |
| ▸ | MMP9 | P14780 | 5/20 | 0.58 |
| ▸ | MMP13 | P45452 | 5/20 | 0.58 |
| ▸ | MMP1 | P03956 | 4/20 | 0.58 |
| ▸ | MMP7 | P09237 | 4/20 | 0.58 |
| ▸ | MMP8 | P22894 | 4/20 | 0.58 |
| ▸ | MMP14 | P50281 | 4/20 | 0.58 |
| ▸ | ADAM10 | O14672 | 3/20 | 0.58 |
| ▸ | MMP15 | P51511 | 1/20 | 0.53 |
| ▸ | MMP16 | P51512 | 1/20 | 0.53 |
| ▸ | ADAM33 | Q9BZ11 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681197 | 0.88 | ADAM17 (0.63) | ADAM17MMP3MMP2MMP9MMP13 | |
| SCHEMBL6682617 | 0.80 | ADAM17 (0.54) | ADAM17MMP3MMP2MMP9MMP13 | |
| Trifluoroacetic Acid SCHEMBL7238317 | 0.80 | ADAM17 (0.62) | ADAM17MMP3MMP2MMP9MMP13 | |
| SCHEMBL6684728 | 0.79 | ADAM17 (0.53) | ADAM17MMP3MMP2MMP9MMP13 | |
| SCHEMBL6685989 | 0.79 | ADAM17 (0.52) | ADAM17MMP3MMP2MMP9MMP13 | |
| SCHEMBL5926615 | 0.78 | ADAM17 (0.70) | ADAM17MMP3MMP2MMP9MMP13 | |
| SCHEMBL5926040 | 0.78 | ADAM17 (0.67) | ADAM17MMP3MMP2MMP9MMP13 | |
| SCHEMBL5926043 | 0.78 | ADAM17 (0.69) | ADAM17MMP3MMP2MMP9MMP13 | |
| SCHEMBL6692496 | 0.77 | ADAM17 (0.47) | ADAM17MMP3MMP2MMP9MMP13 | |
| SCHEMBL7087215 | 0.77 | ADAM17 (0.76) | ADAM17MMP3MMP2MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060212-A1 | ANTI-INFLAMMATORY COATING FOR IMPLANTABLE MEDICAL DEVICES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-07-22 | — | — | WO | claimed |