Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.74 |
| ▸ | NPC1 | O15118 | 9/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.74 |
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | ELANE | P08246 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | MMP2 | P08253 | 2/20 | 0.58 |
| ▸ | MMP9 | P14780 | 2/20 | 0.58 |
| ▸ | MMP8 | P22894 | 2/20 | 0.58 |
| ▸ | MMP13 | P45452 | 2/20 | 0.58 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.55 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.55 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7921287 | 0.89 | RAB9A (0.82) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL2491306 | 0.87 | MMP2 (0.72) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL2243126 | 0.85 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL30002727 | 0.85 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL6682494 | 0.85 | RAB9A (0.67) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL4508204 | 0.85 | RAB9A (0.81) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL4512191 | 0.85 | RAB9A (0.67) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL28686681 | 0.85 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL29531637 | 0.85 | RAB9A (0.67) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL13767161 | 0.84 | RAB9A (0.67) | RAB9ANPC1SMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004067480-A2 | SUBSTITUTED PHENYLUREA DERIVATIVES AS HDAC INHIBITORS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-08-12 | — | — | WO | disclosed |
| WO-2004067480-A2 | SUBSTITUTED PHENYLUREA DERIVATIVES AS HDAC INHIBITORS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-08-12 | — | — | WO | disclosed |