SCHEMBL6686898

SCHEMBL6686898

COC(=O)c1cc(Cl)c(N)c(Cl)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA14 Q9ULX7 2/20 0.52
KDM4E B2RXH2 5/20 0.50
GAA P10253 5/20 0.50
LMNA P02545 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
XDH P47989 2/20 0.50
POLB P06746 1/20 0.50
NFKB1 P19838 1/20 0.50
GFER P55789 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50
FUT7 Q11130 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ALDH1A1 P00352 8/20 0.47
MAPT P10636 5/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31473460 0.90 KDM4E (0.51) CA12CA1CA2CA7CA9
SCHEMBL1759210 0.90 KDM4E (0.51) CA12CA1CA2CA7CA9
SCHEMBL25114613 0.89 GAA (0.58) CA12CA1CA2CA7CA9
SCHEMBL8060962 0.89 CA12 (0.46) CA12CA1CA2CA7CA9
SCHEMBL3717095 0.87 CA1 (0.44) CA12CA1CA2CA7CA9
SCHEMBL20762798 0.87 GAA (0.53) CA12CA1CA2CA7CA9
SCHEMBL24901830 0.87 GAA (0.47) CA12CA1CA2CA7CA9
SCHEMBL27214450 0.87 CA1 (0.44) CA12CA1CA2CA7CA9
SCHEMBL15358059 0.83 NOTUM (0.49) CA12CA1CA2CA7CA9
SCHEMBL8336066 0.83 CA1 (0.56) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026101423-A1 PHOTOSWITCHABLE CHEMICAL INDUCED DIMERIZATION SYSTEMS FOR CONTROL OF CELLULAR ACTIVITIES WITH LIGHT WU YAOWEN (SE) 2026-05-15 WO disclosed
EP-2826474-B1 USE OF SUBSTITUTED DIPHENYLAMINE COMPOUNDS IN PREPARING ANTI-TUMOUR DRUGS SINOCHEM CORP (CN) 2021-05-26 EP disclosed
EP-3491922-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO Dow AgroSciences LLC (US) 2019-06-05 EP disclosed
US-20180370905-A1 Compounds Useful for the Treatment of Metabolic Disorders and Synthesis of the Same NORTH CAROLINA CENTRAL UNIV (US) 2018-12-27 US disclosed
CN-109071484-A Molecule with desinsection effectiveness, and intermediate relevant to these molecules, composition and method 美国陶氏益农公司 2018-12-21 CN disclosed
EP-3408262-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO Dow Agrosciences LLC (US) 2018-12-05 EP disclosed
US-10005720-B2 Compounds useful for the treatment of metabolic disorders and synthesis of the same NORTH CAROLINA CENTRAL UNIVERSITY (US) 2018-06-26 US disclosed
US-10005720-B2 Compounds useful for the treatment of metabolic disorders and synthesis of the same NORTH CAROLINA CENTRAL UNIVERSITY (US) 2018-06-26 US disclosed
US-10005720-B2 Compounds useful for the treatment of metabolic disorders and synthesis of the same NORTH CAROLINA CENTRAL UNIVERSITY (US) 2018-06-26 US disclosed
EP-2934142-B1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2018-01-31 EP disclosed
EP-0230532-B1 2-[(3,5-Dihalo-4-Aminobenzyl)] Imidazolines ABBOTT LABORATORIES (US) 1990-09-26 EP disclosed
EP-0294229-A2 Novel heterocyclic pesticidal compounds THE WELLCOME FOUNDATION LIMITED (GB) 1988-12-07 EP disclosed
EP-0279698-A2 Pesticidal compounds THE WELLCOME FOUNDATION LIMITED (GB) 1988-08-24 EP disclosed
EP-0230532-A1 2-[(3,5-Dihalo-4-Aminobenzyl)] Imidazolines ABBOTT LABORATORIES (US) 1987-08-05 EP disclosed
US-4665095-A Use of 2-[(3,5-dihalo-4-aminobenzyl)]imidazolines to stimulate alpha-1 adrenergic receptors and to treat nasal congestion ABBOTT LABORATORIES (US) 1987-05-12 US disclosed
EP-0107306-B1 IMIDAZOLINE DERIVATIVES BEECHAM GROUP PLC (GB) 1986-04-30 EP disclosed
US-4505926-A GASTROINTESTINAL DISORDERS ANTIDIARRHEA BEECHAM GROUP P.L.C. (GB) 1985-03-19 US disclosed
EP-0107306-A1 Imidazoline derivatives BEECHAM GROUP PLC (GB) 1984-05-02 EP disclosed
US-4375478-A ANTICHOLESTEROL AGENTS ABBOTT LABORATORIES (US) 1983-03-01 US disclosed
US-3960571-A 1-PHENYL-2-PYRAZOL-5-ONE MAGENTA COLOR FORMING COUPLER Fuji Photo Film Co., Ltd. (JA) 1976-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10005720-B2 Compounds useful for the treatment of metabolic disorders and synthesis of the same GLS2, PC, GLS CA12 1478/4885CA1 1045/4885CA2 1038/4885
US-20180370905-A1 Compounds Useful for the Treatment of Metabolic Disorders and Synthesis of the Same GLS2, PC, GLS CA12 1478/4885CA1 1045/4885CA2 1038/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.