Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6690839 | 0.87 | MAPT (0.72) | MAPTNPC1L3MBTL1RAB9ATSHR | |
| SCHEMBL6688798 | 0.83 | MAPT (0.70) | MAPTNPC1L3MBTL1RAB9ATSHR | |
| SCHEMBL6688827 | 0.83 | TSHR (0.61) | MAPTNPC1L3MBTL1RAB9ATSHR | |
| SCHEMBL6687343 | 0.81 | MAPT (1.00) | MAPTNPC1L3MBTL1RAB9ATSHR | |
| SCHEMBL6686975 | 0.80 | ALDH1A1 (0.64) | MAPTNPC1L3MBTL1RAB9ATSHR | |
| SCHEMBL6690858 | 0.78 | ALDH1A1 (0.54) | MAPTNPC1L3MBTL1RAB9ATSHR | |
| SCHEMBL24856146 | 0.73 | TSHR (0.66) | MAPTTSHRNPSR1ALDH1A1POLB | |
| SCHEMBL6689688 | 0.71 | ALDH1A1 (0.76) | MAPTNPC1L3MBTL1RAB9ATSHR | |
| SCHEMBL6686970 | 0.70 | MAPT (0.74) | MAPTNPC1L3MBTL1RAB9ATSHR | |
| SCHEMBL6691444 | 0.70 | TSHR (0.46) | MAPTNPC1L3MBTL1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096808-A1 | TRIAZINE COMPOUNDS AND THEIR USE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-11-11 | — | — | WO | claimed |
| WO-2004096808-A1 | TRIAZINE COMPOUNDS AND THEIR USE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-11-11 | — | — | WO | disclosed |