Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686983 | 0.70 | MAPT (0.68) | TSHRNPSR1MAPTALDH1A1CNR1 | |
| SCHEMBL6688827 | 0.69 | TSHR (0.61) | TSHRNPSR1MAPTALDH1A1CNR1 | |
| SCHEMBL6686975 | 0.66 | ALDH1A1 (0.64) | TSHRNPSR1MAPTALDH1A1CNR1 | |
| SCHEMBL6690858 | 0.65 | ALDH1A1 (0.54) | TSHRNPSR1MAPTALDH1A1CNR1 | |
| SCHEMBL24856146 | 0.64 | TSHR (0.66) | TSHRNPSR1MAPTALDH1A1CNR1 | |
| SCHEMBL6683727 | 0.62 | MAPT (0.74) | TSHRNPSR1MAPTALDH1A1CNR1 | |
| SCHEMBL16357277 | 0.61 | TSHR (0.80) | TSHRNPSR1MAPTALDH1A1CNR1 | |
| SCHEMBL10016582 | 0.60 | MAPT (1.00) | TSHRNPSR1MAPTALDH1A1CNR1 | |
| SCHEMBL6690839 | 0.59 | MAPT (0.72) | TSHRNPSR1MAPTALDH1A1POLB | |
| SCHEMBL6689688 | 0.59 | ALDH1A1 (0.76) | TSHRNPSR1MAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096808-A1 | TRIAZINE COMPOUNDS AND THEIR USE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-11-11 | — | — | WO | disclosed |