SCHEMBL6686992 — predicted protein targets

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	CTSL	P07711	17/20	0.51

▸	CTSS	P25774	15/20	0.51

▸	CTSK	P43235	11/20	0.51

▸	RPLP1	P05386	2/20	0.40

▸	RPLP0	P05388	2/20	0.40

▸	RPS17	P08708	2/20	0.40

▸	RPSA	P08865	2/20	0.40

▸	RPS2	P15880	2/20	0.40

▸	RPL35A	P18077	2/20	0.40

▸	RPL7	P18124	2/20	0.40

▸	RPL17	P18621	2/20	0.40

▸	RPS4Y1	P22090	2/20	0.40

▸	RPS3	P23396	2/20	0.40

▸	RPS12	P25398	2/20	0.40

▸	RPL13	P26373	2/20	0.40

▸	RPL10	P27635	2/20	0.40

▸	RPL12	P30050	2/20	0.40

▸	RPL9; RPL9P7; RPL9P8; RPL9P9	P32969	2/20	0.40

▸	RPL22	P35268	2/20	0.40

▸	RPL4	P36578	2/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6687577	0.71	CTSL (0.72)	CTSLCTSSCTSK
SCHEMBL4795897	0.71	CTSL (0.64)	CTSLCTSSCTSK
SCHEMBL4801325	0.71	CTSL (0.64)	CTSLCTSSCTSK
SCHEMBL4795900	0.71	CTSL (0.64)	CTSLCTSSCTSK
SCHEMBL4795899	0.71	CTSL (0.64)	CTSLCTSSCTSK
SCHEMBL25194772	0.70	RPLP1 (0.49)	RPLP1RPLP0RPS17RPSARPS2
SCHEMBL4206948	0.69	TAS1R3 (0.75)	CTSLCTSSCTSK
SCHEMBL4206947	0.69	TAS1R3 (0.75)	CTSLCTSSCTSK
SCHEMBL4801053	0.69	CTSL (0.56)	CTSLCTSSCTSK
SCHEMBL4800332	0.69	CTSL (0.56)	CTSLCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2004084843-A2	INHIBITORS OF CATHEPSIN S	IRM LLC (BM)	2004-10-07	—	—	WO	disclosed