Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687023 | 1.00 | HTR6 (0.64) | HTR6 | |
| SCHEMBL6693519 | 1.00 | HTR6 (0.64) | HTR6 | |
| SCHEMBL6707100 | 0.84 | HTR6 (0.61) | HTR6 | |
| Hydrochloric Acid SCHEMBL6709094 | 0.84 | HTR6 (0.62) | HTR6 | |
| SCHEMBL6707678 | 0.82 | HTR6 (0.58) | HTR6 | |
| SCHEMBL6753284 | 0.81 | HTR6 (0.57) | HTR6 | |
| SCHEMBL6038252 | 0.81 | HTR6 (0.62) | HTR6 | |
| SCHEMBL6038266 | 0.79 | HTR6 (0.84) | HTR6 | |
| SCHEMBL801073 | 0.78 | HTR6 (1.00) | HTR6 | |
| SCHEMBL6038268 | 0.78 | HTR6 (0.67) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040162332-A1 | Arylsulphonyl substituted-tetrahydro-and hexahydro-carbazoles | PHARMACIA & UPJOHN COMPANY | 2004-08-19 | — | — | US | disclosed |
| EP-1434578-A1 | ARYLSULPHONYL-SUBSTITUTED TETRAHYDRO- AND HEXAHYDRO-CARBAZOLES AS 5-HT-6 RECEPTOR LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 2004-07-07 | — | — | EP | disclosed |
| US-6727274-B2 | Arylsulphonyl substituted-tetrahydro- and hexahydro-carbazoles | PHARMACIA & UPJOHN COMPANY | 2004-04-27 | — | — | US | disclosed |
| US-20030100596-A1 | Arylsulphonyl substituted-tetrahydro- and hexahydro-carbazoles | PHARMACIA & UPJOHN COMPANY | 2003-05-29 | — | — | US | disclosed |
| WO-2003030901-A1 | ARYLSULPHONYL-SUBSTITUTED TETRAHYDRO- AND HEXAHYDRO-CARBAZOLES AS 5-HT-6 RECEPTOR LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 2003-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030100596-A1 | Arylsulphonyl substituted-tetrahydro- and hexahydro-carbazoles | HTR6, HTR3B, HTR3C | HTR6 1/4885 |
| US-20040162332-A1 | Arylsulphonyl substituted-tetrahydro-and hexahydro-carbazoles | HTR6, HTR3B, HTR3C | HTR6 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.