Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 3/20 | 0.31 |
| ▸ | THRA | P10827 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1303608 | 0.91 | HSP90AB1 (0.32) | IKBKBRARA | |
| SCHEMBL6687711 | 0.85 | — | — | |
| SCHEMBL1303570 | 0.84 | IKBKB (0.31) | IKBKBRARA | |
| SCHEMBL1303224 | 0.84 | — | — | |
| SCHEMBL1303522 | 0.83 | ALDH1A1 (0.34) | IKBKBRARARARG | |
| SCHEMBL5498802 | 0.79 | THRB (0.49) | THRBTHRA | |
| SCHEMBL1303158 | 0.78 | CA1 (0.33) | — | |
| SCHEMBL6389172 | 0.77 | — | — | |
| SCHEMBL6691080 | 0.76 | SRC (0.35) | THRBTHRA | |
| SCHEMBL6690661 | 0.75 | HSP90AB1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004062661-A1 | 2-‘5-(5-CARBAMIMIDOYL-1H-HETEROARYL)-6-HYDROXYBIPHENYL-3-YL!- CARBOXYLIC ACID DERIVATIVES AS FACTOR VIIA INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2004-07-29 | — | — | WO | disclosed |