Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1843106 | 0.91 | ALDH1A1 (0.45) | ALDH1A1CYP3A4MAPTKMT2AMEN1 | |
| SCHEMBL1839009 | 0.89 | ALDH1A1 (0.43) | ALDH1A1CYP3A4MAPTKMT2AMEN1 | |
| SCHEMBL13435780 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CYP3A4MAPTKMT2AMEN1 | |
| SCHEMBL1838514 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CYP3A4MAPTKMT2AMEN1 | |
| SCHEMBL1842314 | 0.76 | ALDH1A1 (0.44) | ALDH1A1CYP3A4MAPTKMT2AMEN1 | |
| SCHEMBL3384398 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2AMEN1HPGD | |
| SCHEMBL1840324 | 0.75 | ALDH1A1 (0.43) | ALDH1A1CYP3A4MAPTKMT2AMEN1 | |
| SCHEMBL1840993 | 0.75 | ALDH1A1 (0.43) | ALDH1A1CYP3A4MAPTKMT2AMEN1 | |
| SCHEMBL1841462 | 0.75 | ALDH1A1 (0.46) | ALDH1A1CYP3A4MAPTKMT2AMEN1 | |
| SCHEMBL1839935 | 0.75 | ALDH1A1 (0.43) | ALDH1A1CYP3A4MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004062361-A2 | SPIRO COMPOUNDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-07-29 | — | — | WO | disclosed |