Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6855861 | 0.92 | NPC1 (0.53) | CNR2LMNAMAPTALDH1A1HTT | |
| SCHEMBL6694669 | 0.89 | MAPK1 (0.43) | CNR2LMNAMAPTALDH1A1HTT | |
| SCHEMBL6694633 | 0.89 | LMNA (0.41) | CNR2LMNAMAPTALDH1A1HTT | |
| SCHEMBL6688792 | 0.88 | MAPT (0.48) | CNR2LMNAMAPTALDH1A1HTT | |
| SCHEMBL6691125 | 0.87 | MEN1 (0.45) | CNR2LMNAMAPTALDH1A1HTT | |
| SCHEMBL6688574 | 0.86 | SMN1; SMN2 (0.39) | CNR2LMNAMAPTALDH1A1HTT | |
| SCHEMBL6686728 | 0.85 | LMNA (0.41) | CNR2LMNAMAPTALDH1A1HTT | |
| SCHEMBL14366844 | 0.85 | ALDH1A1 (0.61) | CNR2LMNAMAPTALDH1A1HTT | |
| SCHEMBL6689688 | 0.74 | ALDH1A1 (0.76) | LMNAMAPTALDH1A1HTTHIF1A | |
| SCHEMBL15076954 | 0.74 | MAPT (0.41) | CNR2LMNAMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096808-A1 | TRIAZINE COMPOUNDS AND THEIR USE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-11-11 | — | — | WO | claimed |
| WO-2004096808-A1 | TRIAZINE COMPOUNDS AND THEIR USE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-11-11 | — | — | WO | disclosed |