Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.61 |
| ▸ | DRD3 | P35462 | 2/20 | 0.59 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD5 | P21918 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | PRCP | P42785 | 1/20 | 0.50 |
| ▸ | EBP | Q15125 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL26666899 | 0.98 | DRD2 (0.68) | DRD2SIGMAR1SLC6A4DRD3DRD1 | |
| Hydrochloric Acid SCHEMBL30689998 | 0.98 | DRD2 (0.68) | DRD2SIGMAR1SLC6A4DRD3DRD1 | |
| SCHEMBL6655242 | 0.89 | DRD2 (0.63) | DRD2SIGMAR1SLC6A4DRD3DRD1 | |
| SCHEMBL28322710 | 0.88 | DRD2 (0.52) | DRD2SIGMAR1SLC6A4DRD3DRD1 | |
| SCHEMBL20680005 | 0.85 | SLC18A3 (0.67) | DRD2SIGMAR1SLC6A4DRD3DRD1 | |
| SCHEMBL7313051 | 0.84 | DRD3 (0.73) | DRD2SIGMAR1DRD3DRD1DRD4 | |
| SCHEMBL7349090 | 0.84 | DRD3 (0.73) | DRD2SIGMAR1DRD3DRD1DRD4 | |
| Hydrochloric Acid SCHEMBL7317716 | 0.83 | DRD3 (0.71) | DRD2SIGMAR1DRD3DRD1DRD4 | |
| SCHEMBL2634374 | 0.83 | DRD2 (0.57) | DRD2SIGMAR1SLC6A4DRD3 | |
| SCHEMBL328311 | 0.82 | QDPR (0.53) | DRD2SIGMAR1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004064774-A2 | DNA ENCODING A HUMAN MELANIN CONCENTRATING HORMONE RECEPTOR (MCH1) AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2004-08-05 | — | — | WO | disclosed |
| EP-1246847-A2 | DNA ENCODING A HUMAN MELANIN CONCENTRATING HORMONE RECEPTOR (MCH1) AND USES THEREOF | Synaptic Pharmaceutical Corporation (US) | 2002-10-09 | — | — | EP | disclosed |
| WO-2002002744-A2 | DNA ENCODING A HUMAN MELANIN CONCENTRATING HORMONE RECEPTOR (MCH1) AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2002-01-10 | — | — | WO | disclosed |