Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687567 | 0.90 | PPARG (0.42) | ITGA4ITGB7CD274PPARGPTPRZ1 | |
| SCHEMBL6687562 | 0.90 | PPARG (0.42) | ITGA4ITGB7CD274PPARGPTPRZ1 | |
| SCHEMBL6689339 | 0.88 | PTPRZ1 (0.43) | CD274PPARGPPARAPPARDPTPRZ1 | |
| SCHEMBL6689649 | 0.88 | MAOB (0.51) | PPARGPTPRZ1MAOBMAOA | |
| SCHEMBL6687537 | 0.88 | PTPRZ1 (0.43) | CD274PPARGPPARAPPARDPTPRZ1 | |
| SCHEMBL6688970 | 0.86 | MAOB (0.52) | CD274PPARAPTPRZ1MAOBMAOA | |
| SCHEMBL6690781 | 0.86 | MAOB (0.52) | CD274PPARAPTPRZ1MAOBMAOA | |
| SCHEMBL6691341 | 0.86 | PTPRZ1 (0.53) | PPARGPTPRZ1MAOBMAOA | |
| SCHEMBL6685530 | 0.81 | FFAR4 (0.48) | CD274PPARGPPARAFFAR1FFAR4 | |
| SCHEMBL6685527 | 0.81 | FFAR4 (0.48) | CD274PPARGPPARAFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |