Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.52 |
| ▸ | MAOA | P21397 | 4/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.48 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6688970 | 1.00 | MAOB (0.52) | MAOBMAOASCN9APTPRZ1CD274 | |
| SCHEMBL6688211 | 0.90 | PTPRZ1 (0.46) | MAOBMAOAPTPRZ1CD274PPARA | |
| SCHEMBL6688209 | 0.90 | PTPRZ1 (0.46) | MAOBMAOAPTPRZ1CD274PPARA | |
| SCHEMBL6687537 | 0.89 | PTPRZ1 (0.43) | MAOBMAOASCN9APTPRZ1CD274 | |
| SCHEMBL6689339 | 0.89 | PTPRZ1 (0.43) | MAOBMAOASCN9APTPRZ1CD274 | |
| SCHEMBL6686474 | 0.89 | MAOB (0.47) | MAOBMAOASCN9APTPRZ1CD274 | |
| SCHEMBL6686473 | 0.89 | MAOB (0.47) | MAOBMAOASCN9APTPRZ1CD274 | |
| SCHEMBL6687535 | 0.86 | ITGA4 (0.44) | MAOBMAOAPTPRZ1CD274PPARA | |
| SCHEMBL6685873 | 0.85 | MAOB (0.61) | MAOBMAOASCN9APTPRZ1HRH3 | |
| SCHEMBL6685877 | 0.85 | MAOB (0.61) | MAOBMAOASCN9APTPRZ1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |