Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 7/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Phenyl-Butylamine SCHEMBL6687616 | 0.84 | SLC7A5 (0.55) | SLC7A5EPHX1MAOADRD2DRD4 | |
| SCHEMBL8321773 | 0.81 | SLC7A5 (0.50) | SLC7A5DAODHODHALDH1A1TSHR | |
| SCHEMBL6230413 | 0.80 | SLC7A5 (0.49) | SLC7A5DAODHODHALDH1A1TSHR | |
| SCHEMBL2097292 | 0.80 | SLC7A5 (0.49) | SLC7A5DAODHODHALDH1A1TSHR | |
| SCHEMBL2024806 | 0.77 | SLC7A5 (0.48) | SLC7A5DAODHODHALDH1A1TSHR | |
| SCHEMBL28949186 | 0.72 | AKT2 (0.49) | SLC7A5DAODHODHGRM2GPR84 | |
| SCHEMBL12706130 | 0.71 | CYP1A2 (0.61) | SLC7A5DAOALDH1A1TSHREPHX1 | |
| SCHEMBL28447540 | 0.70 | SLC7A5 (0.44) | SLC7A5ALDH1A1TSHREPHX1 | |
| SCHEMBL718129 | 0.70 | TAAR1 (0.55) | DAO | |
| SCHEMBL1729187 | 0.70 | SLC2A1 (0.55) | SLC7A5ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071445-A2 | 2-(AMINOMETHYL)ARYLAMIDE ANALGESICS | PHARMACOPEIA DRUG DISCOVERY, INC. (US) | 2004-08-26 | — | — | WO | disclosed |