Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 9/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687613 | 0.84 | SLC7A5 (0.45) | SLC7A5MAOAEPHX1DRD2DRD4 | |
| SCHEMBL8321773 | 0.79 | SLC7A5 (0.50) | SLC7A5MAOAKIF11 | |
| SCHEMBL9804440 | 0.78 | SLC7A5 (0.41) | SLC7A5EPHX1DRD2DRD4DRD3 | |
| SCHEMBL9492405 | 0.78 | CETP (0.50) | — | |
| SCHEMBL2097292 | 0.78 | SLC7A5 (0.49) | SLC7A5MAOAKIF11 | |
| SCHEMBL6230413 | 0.78 | SLC7A5 (0.49) | SLC7A5MAOAKIF11 | |
| SCHEMBL11133727 | 0.76 | SLC7A5 (0.54) | SLC7A5MAOA | |
| SCHEMBL9493734 | 0.75 | CETP (0.40) | SLC7A5EPHX1 | |
| SCHEMBL2024806 | 0.74 | SLC7A5 (0.48) | SLC7A5KIF11 | |
| SCHEMBL13098056 | 0.74 | LTA4H (0.50) | GRIN2BEPHX1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071445-A2 | 2-(AMINOMETHYL)ARYLAMIDE ANALGESICS | PHARMACOPEIA DRUG DISCOVERY, INC. (US) | 2004-08-26 | — | — | WO | disclosed |