SCHEMBL718129

SCHEMBL718129

NCCc1ccc(OC(F)(F)F)cc1

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.55
MAOB P27338 7/20 0.53
DAO P14920 1/20 0.47
KIF11 P52732 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL29202239 0.98 TAAR1 (0.53) TAAR1MAOBDAOKIF11
Iodide SCHEMBL29202228 0.98 TAAR1 (0.53) TAAR1MAOBDAOKIF11
Hydrochloric Acid SCHEMBL2445996 0.98 MAOB (0.56) TAAR1MAOB
SCHEMBL5560530 0.89 MAOB (0.69) MAOB
SCHEMBL2024806 0.88 SLC7A5 (0.48) TAAR1MAOBDAOKIF11
Acetic Acid SCHEMBL29202197 0.88 DHODH (0.51) TAAR1MAOB
SCHEMBL8321773 0.86 SLC7A5 (0.50) MAOBDAOKIF11
SCHEMBL5185022 0.85 LTA4H (0.49)
SCHEMBL2097292 0.85 SLC7A5 (0.49) MAOBDAOKIF11
SCHEMBL6230413 0.85 SLC7A5 (0.49) MAOBDAOKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119371337-A Metal halide perovskite nanocrystalline resistant to heat-induced fluorescence quenching, and preparation method and application thereof 华南理工大学 2025-01-28 CN claimed
CN-117043140-A Substituted pyrrolidin-2-ones, salts thereof and their use as herbicidal active substances 拜耳公司 2023-11-10 CN claimed
EP-1219591-B1 Process for preparing 2-(4-trifluoromethoxyphenyl)ethylamine BAYER CHEMICALS AG (DE) 2004-03-31 EP claimed
US-6441239-B1 Process for preparing 2-(4-trifluoromethoxyphenyl)ethylamine and 4-bromomethyl-and 4-chloromethyl-1-trifluoromethoxybenzene BAYER AKTIENGESELLSCHAFT (DE) 2002-08-27 US claimed
EP-1219591-A1 Process for preparing 2-(4-trifluoromethoxyphenyl)ethylamine and 4-bromomethyl- and 4-chloromethyl- -1trifluoromethoxybenzene Bayer Aktiengesellschaft (DE) 2002-07-03 EP claimed
US-20020082454-A1 PROCESS FOR PREPARING 2-(4-TRIFLUOROMETHOXYPHENYL)ETHYLAMINE AND 4-BROMOMETHYL-AND 4-CHLOROMETHYL-1-TRIFLUOROMETHOXYBENZENE LANXESS DEUTSCHLAND GMBH (DE) 2002-06-27 US claimed
US-20020058788-A1 Facile deprotection of Fmoc protected amino groups DISCOVERY PARTNERS INTERNATIONAL, INC. 2002-05-16 US claimed
US-20250144094-A1 THIOPHENE ULK1/2 INHIBITORS AND THEIR USE THEREOF ERASCA, INC. 2025-05-08 US disclosed
WO-2025054339-A1 TRIAZOLOPYRIDINE COMPOUNDS AS INHIBITORS OF KIT ARCUS BIOSCIENCES, INC. (US) 2025-03-13 WO disclosed
CN-119371337-A Metal halide perovskite nanocrystalline resistant to heat-induced fluorescence quenching, and preparation method and application thereof 华南理工大学 2025-01-28 CN disclosed
CN-119072141-A Long-life perovskite light-emitting diode and preparation method thereof 南京工业大学 2024-12-03 CN disclosed
EP-4433059-A1 THIOPHENE ULK1/2 INHIBITORS AND THEIR USE THEREOF Erasca, Inc. (US) 2024-09-25 EP disclosed
CN-117682967-A Inhibitor for targeting c-Myc and application thereof 四川大学 2024-03-12 CN disclosed
EP-0981516-A1 SUBSTITUTED TETRAHYDROISOQUINOLINE DERIVATIVES AS MODULATORS OF DOPAMINE D?3 RECEPTORS SMITHKLINE BEECHAM PLC (GB) 2000-03-01 EP disclosed
EP-0922035-A1 TETRAHYDROISOQUINOLINE DERIVATIVES AND THEIR PHARMACEUTICAL USE SMITHKLINE BEECHAM PLC (GB) 1999-06-16 EP disclosed
WO-1998049145-A1 SUBSTITUTED TETRAHYDROISOQUINOLINE DERIVATIVES AS MODULATORS OF DOPAMINE D3 RECEPTORS SMITHKLINE BEECHAM PLC (GB) 1998-11-05 WO disclosed
WO-1998006699-A1 TETRAHYDROISOQUINOLINE DERIVATIVES AND THEIR PHARMACEUTICAL USE SMITHKLINE BEECHAM PLC (GB) 1998-02-19 WO disclosed
EP-0665225-B1 4-Phenethylamino pyrimidine derivative, process for preparing the same and agricultural and horticultural chemical for controlling noxious organisms containing the same UBE INDUSTRIES (JP) 1996-11-27 EP disclosed
US-5498612-A INSECTICIDE, ACARICIDE, FUNGICIDE, NEMATOCIDE UBE INDUSTRIES, LTD. (JP) 1996-03-12 US disclosed
EP-0665225-A1 4-Phenethylamino pyrimidine derivative, process for preparing the same and agricultural and horticultural chemical for controlling noxious organisms containing the same UBE INDUSTRIES, LTD. (JP) 1995-08-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250144094-A1 THIOPHENE ULK1/2 INHIBITORS AND THEIR USE THEREOF ULK1, ULK2, ULK3 TAAR1 4124/4885MAOB 4469/4885DAO 4525/4885
US-20020058788-A1 Facile deprotection of Fmoc protected amino groups DNPEP, LNPEP, NPEPPS TAAR1 1082/4885MAOB 1190/4885DAO 33/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.