Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 4/20 | 0.71 |
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.71 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.71 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.71 |
| ▸ | GMNN | O75496 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | TP53 | P04637 | 2/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.71 |
| ▸ | BLM | P54132 | 2/20 | 0.71 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | THPO | P40225 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5363455 | 0.89 | MAPT (0.58) | CSNK1DMAPTMAPK1CSNK1A1CSNK1E | |
| SCHEMBL5358059 | 0.85 | MDM2 (0.75) | CSNK1DMAPTMAPK1CSNK1A1CSNK1E | |
| SCHEMBL5368858 | 0.85 | MAPT (0.62) | CSNK1DMAPTMAPK1CSNK1A1CSNK1E | |
| SCHEMBL5358330 | 0.83 | MAPT (0.52) | CSNK1DMAPTMAPK1CSNK1A1CSNK1E | |
| Ic261 SCHEMBL2786157 | 0.83 | CSNK1D (1.00) | CSNK1DMAPTMAPK1CSNK1A1CSNK1E | |
| Ic261 SCHEMBL29467414 | 0.83 | CSNK1D (1.00) | CSNK1DMAPTMAPK1CSNK1A1CSNK1E | |
| Ic261 SCHEMBL3697594 | 0.83 | CSNK1D (1.00) | CSNK1DMAPTMAPK1CSNK1A1CSNK1E | |
| Ic261 SCHEMBL905701 | 0.83 | CSNK1D (1.00) | CSNK1DMAPTMAPK1CSNK1A1CSNK1E | |
| SCHEMBL5368424 | 0.83 | MDM2 (0.61) | CSNK1DMAPTMAPK1GMNNLMNA | |
| SCHEMBL5358413 | 0.82 | RET (0.73) | MAPTMAPK1GMNNLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069998-A2 | OXINDOLE DERIVATIVES AS ANTIMICROBIAL AGENTS | ARROW THERAPEUTICS LIMITED (GB) | 2004-08-19 | — | — | WO | disclosed |