SCHEMBL6687964

SCHEMBL6687964

CCc1cccc2[nH]c(-c3ccccc3)nc12

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GRIN2B Q13224 3/20 0.60
CYP1A2 P05177 1/20 0.60
CYP2D6 P10635 1/20 0.60
DHODH Q02127 5/20 0.56
PARP1 P09874 4/20 0.56
GAA P10253 6/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
MGAM O43451 5/20 0.49
SI P14410 5/20 0.49
MGAM2 Q2M2H8 5/20 0.49
RPS6KA3 P51812 1/20 0.47
TNKS O95271 1/20 0.47
TNKS2 Q9H2K2 1/20 0.47
TP53 P04637 1/20 0.46
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3969183 0.87 GRIN2B (0.60) GRIN2BCYP1A2CYP2D6DHODHPARP1
SCHEMBL24368227 0.84 PKN1 (0.61) GRIN2BCYP1A2CYP2D6DHODHPARP1
SCHEMBL8816937 0.83 CYP1A2 (0.59) GRIN2BCYP1A2CYP2D6DHODHPARP1
SCHEMBL7210788 0.81 GRIN2B (0.58) GRIN2BCYP1A2CYP2D6DHODHPARP1
SCHEMBL7211155 0.81 GRIN2B (0.58) GRIN2BCYP1A2CYP2D6DHODHPARP1
SCHEMBL8814837 0.81 GRIN2B (0.54) GRIN2BCYP1A2CYP2D6DHODHPARP1
SCHEMBL7668672 0.80 GAA (0.46) GRIN2BCYP1A2CYP2D6DHODHPARP1
Hydrochloric Acid SCHEMBL8816892 0.80 GRIN2B (0.53) GRIN2BCYP1A2CYP2D6DHODHPARP1
SCHEMBL5202972 0.78 DHODH (0.49) GRIN2BCYP1A2CYP2D6DHODHPARP1
SCHEMBL5074029 0.78 MGAM (0.76) PARP1GAANPC1RAB9AMGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004078874-A2 NOVEL DYE COMPLEXES AND USE THEREOF IN IMAGING MEMBERS AND METHODS POLAROID CORPORATION (US) 2004-09-16 WO claimed
CN-106866543-B A method of benzimidazole compound is catalyzed and synthesized under microwave radiation in water phase 福建医科大学 2019-05-14 CN disclosed
WO-2004078874-A2 NOVEL DYE COMPLEXES AND USE THEREOF IN IMAGING MEMBERS AND METHODS POLAROID CORPORATION (US) 2004-09-16 WO disclosed