Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 3/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7668683 | 0.85 | NPC1 (0.53) | GAANPC1RAB9ACYP1A2MAPT | |
| SCHEMBL7673395 | 0.83 | AURKA (0.54) | GAANPC1RAB9ACYP1A2TP53 | |
| SCHEMBL7670070 | 0.82 | PARP1 (0.52) | GAANPC1RAB9AMAPTTP53 | |
| SCHEMBL6687964 | 0.80 | GRIN2B (0.60) | GAANPC1RAB9ACYP1A2CYP2D6 | |
| SCHEMBL7671242 | 0.73 | HSD17B10 (0.49) | CYP1A2MAPTTP53ALDH1A1POLB | |
| SCHEMBL2823766 | 0.73 | ALDH1A1 (0.64) | GAANPC1RAB9AMAPTTP53 | |
| SCHEMBL6009050 | 0.71 | MAPT (0.54) | GRIN2BMAPTALDH1A1POLBKDM4E | |
| SCHEMBL28306367 | 0.71 | NPC1 (0.50) | GAANPC1RAB9ACYP1A2MAPT | |
| SCHEMBL3969183 | 0.71 | GRIN2B (0.60) | GAANPC1RAB9ACYP1A2CYP2D6 | |
| SCHEMBL11797881 | 0.70 | PLA2G2A (0.43) | MAPTPARP1ALDH1A1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479499-B1 | INHIBITORS OF TUBULIN POLYMERIZATION | NATIONAL SCIENCE COUNCIL (TW) | 2002-11-12 | — | — | US | disclosed |