Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686207 | 0.82 | NAMPT (0.48) | TP53MAPTNPC1RAB9AAGPAT2 | |
| SCHEMBL6688046 | 0.78 | CEPT1 (0.40) | CEPT1NPC1RAB9AAGPAT2POLB | |
| SCHEMBL6086026 | 0.77 | CEPT1 (0.47) | CEPT1TP53MAPTNPC1RAB9A | |
| SCHEMBL6084017 | 0.77 | CEPT1 (0.52) | CEPT1TP53MAPTNPC1RAB9A | |
| SCHEMBL6087191 | 0.76 | CEPT1 (0.51) | CEPT1TP53MAPTNPC1RAB9A | |
| SCHEMBL6086055 | 0.76 | CEPT1 (0.39) | CEPT1MAPTNPC1RAB9AAGPAT2 | |
| SCHEMBL6085513 | 0.75 | CEPT1 (0.58) | CEPT1TP53MAPTAGPAT2RXFP1 | |
| SCHEMBL6086552 | 0.75 | CEPT1 (0.49) | CEPT1TP53MAPTNPC1RAB9A | |
| SCHEMBL6084212 | 0.75 | CEPT1 (0.51) | CEPT1TP53MAPTNPC1RAB9A | |
| SCHEMBL6085859 | 0.74 | CEPT1 (0.51) | CEPT1TP53MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377589-A1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | Pharmacia Italia S.p.A. (IT) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002062804-A1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA S.P.A. (IT) | 2002-08-15 | — | — | WO | disclosed |