Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.40 |
| ▸ | FASN | P49327 | 9/20 | 0.37 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086055 | 0.84 | CEPT1 (0.39) | CEPT1FASNAGPAT2TMEM97HRH4 | |
| SCHEMBL6690576 | 0.83 | NPC1 (0.41) | FASNAGPAT2TMEM97HRH4NPC1 | |
| SCHEMBL6688484 | 0.78 | CEPT1 (0.44) | CEPT1AGPAT2NPC1RAB9APOLB | |
| SCHEMBL6692684 | 0.78 | AGPAT2 (0.41) | CEPT1AGPAT2TOP2ANPC1RAB9A | |
| SCHEMBL6086552 | 0.74 | CEPT1 (0.49) | CEPT1AGPAT2TOP2ANPC1RAB9A | |
| SCHEMBL6086026 | 0.73 | CEPT1 (0.47) | CEPT1AGPAT2NPC1RAB9A | |
| SCHEMBL6084017 | 0.73 | CEPT1 (0.52) | CEPT1AGPAT2TOP2ANPC1RAB9A | |
| SCHEMBL6087191 | 0.72 | CEPT1 (0.51) | CEPT1AGPAT2TOP2ANPC1RAB9A | |
| SCHEMBL6670101 | 0.71 | NPC1 (0.42) | FASNAGPAT2TMEM97HRH4NPC1 | |
| SCHEMBL6084212 | 0.71 | CEPT1 (0.51) | CEPT1AGPAT2NPC1RAB9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377589-A1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | Pharmacia Italia S.p.A. (IT) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002062804-A1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA S.P.A. (IT) | 2002-08-15 | — | — | WO | disclosed |