Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.51 |
| ▸ | ACE | P12821 | 2/20 | 0.51 |
| ▸ | CPA1 | P15085 | 2/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.51 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6688644 | 1.00 | MME (0.51) | MMEACECPA1ACE2ADAM17 | |
| SCHEMBL6688338 | 0.92 | MAOB (0.53) | MMEACECPA1ACE2PPARA | |
| SCHEMBL6688332 | 0.92 | MAOB (0.53) | MMEACECPA1ACE2PPARA | |
| SCHEMBL6691022 | 0.85 | MAOB (0.46) | MAOBMAOASCN9A | |
| SCHEMBL6691028 | 0.85 | MAOB (0.46) | MAOBMAOASCN9A | |
| SCHEMBL6690288 | 0.85 | SMN1; SMN2 (0.46) | MMEACECPA1ACE2PPARA | |
| SCHEMBL6690290 | 0.85 | SMN1; SMN2 (0.46) | MMEACECPA1ACE2PPARA | |
| SCHEMBL6693847 | 0.83 | PTPRZ1 (0.54) | MAOBMAOASCN9A | |
| SCHEMBL6693852 | 0.83 | PTPRZ1 (0.54) | MAOBMAOASCN9A | |
| SCHEMBL8935445 | 0.83 | BCHE (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |