SCHEMBL66887

SCHEMBL66887

[NH]CCO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL359512 0.75
SCHEMBL248177 0.72
SCHEMBL749869 0.71
Ethylene Glycol SCHEMBL1332716 0.63
Ethylene Glycol SCHEMBL8013339 0.63 TSHR (1.00)
Ethylene Glycol SCHEMBL2635018 0.63 TSHR (1.00)
Ethylene Glycol SCHEMBL3 0.63
SCHEMBL190090 0.63
Ethylene Glycol SCHEMBL49878 0.63
Ethylene Glycol SCHEMBL11297158 0.63 TSHR (1.00)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6588 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4392032-A1 MODULATORS OF THE BETA-3 ADRENERGIC RECEPTOR FOR THE TREATMENT OR PREVENTION OF RENAL CYSTIC DISEASE AND CARDIORENAL SYNDROME Arena Pharmaceuticals, Inc. (US) 2024-07-03 EP claimed
WO-2024133200-A1 P2X3 RECEPTOR ANTAGONISTS RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA SPA (IT) 2024-06-27 WO claimed
EP-4389746-A2 P2X3 RECEPTOR ANTAGONISTS Recordati Industria Chimica E Farmaceutica SPA (IT) 2024-06-26 EP claimed
CN-114591318-B Pyrazolo heterocyclic compound, preparation method thereof, pharmaceutical composition and application 中国医学科学院药物研究所 2024-06-21 CN claimed
CN-115466251-B Condensed heterocyclic compound, preparation method, pharmaceutical composition and application thereof 中国医学科学院药物研究所 2024-06-21 CN claimed
CN-114507227-B Benzisothiazole compound, preparation method, pharmaceutical composition and application thereof 中国医学科学院药物研究所 2024-06-21 CN claimed
US-20240199542-A1 SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2024-06-20 US claimed
CN-115108931-B Tofenamic acid derivative and preparation and application thereof 南华大学附属第一医院 2024-06-14 CN claimed
CN-118201916-A Piperazinylsulfonylaryl compounds for the treatment of bacterial infections 豪夫迈·罗氏有限公司 2024-06-14 CN claimed
WO-2024118887-A1 N-PHENYL-PYRAZOLO[1,5-A]PYRIDINE-3-CARBOXAMIDE DERIVATIVES AS WILD TYPE C-KIT KINASE INHIBITORS FOR THE TREATMENT OF URTICARIA BLUEPRINT MEDICINES CORPORATION (US) 2024-06-06 WO claimed
EP-0003640-A2 Antisecretory guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1979-08-22 EP claimed
US-4146604-A STAINING WITH MIXTURE OF FLUORESCENT DYES AND SENSITIZERS BLOCK ENGINEERING, INC. (US) 1979-03-27 US claimed
US-4136033-A DIAZO COUPLERS SANDOZ LTD. (CH) 1979-01-23 US claimed
US-4087597-A Anti-fouling compositions BIOMARINE HANDELSGESELLSCHAFT AG. (FL) 1978-05-02 US claimed
US-4054559-A Reactive disazo monohalogenotriazine dyestuffs NIPPON KAYAKU KABUSHIKI KAISHA (JA) 1977-10-18 US claimed
US-4049661-A FIBER-REACTIVE CIBA-GEIGY AG (CH) 1977-09-20 US claimed
US-4018775-A LIVER DISORDERS WARNER-LAMBERT COMPANY (US) 1977-04-19 US claimed
US-3991257-A ORGANOPHOSPHORUS COMPOUNDS CIBA-GEIGY AG (CH) 1976-11-09 US claimed
US-3956274-A BACTERICIDES ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JA) 1976-05-11 US claimed
US-3940391-A HERBICIDE BAYER AKTIENGESELLSCHAFT (DT) 1976-02-24 US claimed