⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL749869 | 0.87 | — | — | |
| SCHEMBL460354 | 0.84 | — | — | |
| SCHEMBL9478813 | 0.84 | LMNA (0.44) | — | |
| SCHEMBL6507209 | 0.84 | — | — | |
| SCHEMBL9481388 | 0.84 | LMNA (0.44) | — | |
| SCHEMBL9478728 | 0.84 | LMNA (0.44) | — | |
| SCHEMBL1289416 | 0.84 | — | — | |
| SCHEMBL66887 | 0.75 | — | — | |
| 1,4-Butanediol SCHEMBL324322 | 0.68 | SMN1; SMN2 (0.58) | — | |
| 1,4-Butanediol SCHEMBL18642509 | 0.68 | SMN1; SMN2 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1374 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076594-A | Sulfonylpiperazinyl compounds for the treatment of bacterial infections | 豪夫迈·罗氏有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-114450284-B | 6, 7-Dihydro-5H-pyrido [2,3-C ] pyridazine derivatives as BCL-XL protein inhibitors | 法国施维雅药厂 | 2024-05-07 | — | — | CN | claimed |
| CN-117510561-A | Tylosin derivative and preparation method and application thereof | 中国农业科学院饲料研究所 | 2024-02-06 | — | — | CN | claimed |
| EP-4003989-B1 | 6,7-DIHYDRO-5H-PYRIDO[2,3-C]PYRIDAZINE DERIVATIVES AND RELATED COMPOUNDS AS BCL-XL PROTEIN INHIBITORS AND PRO-APOPTOTIC AGENTS FOR TREATING CANCER | SERVIER LAB (FR) | 2023-12-27 | — | — | EP | claimed |
| CN-117126180-A | Biphenyl compound as immunomodulator as well as preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-11-28 | — | — | CN | claimed |
| WO-2023061617-A1 | SULFONYLPIPERAZINYL COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-04-20 | — | — | WO | claimed |
| EP-4003989-A1 | 6,7-DIHYDRO-5H-PYRIDO[2,3-C]PYRIDAZINE DERIVATIVES AND RELATED COMPOUNDS AS BCL-XL PROTEIN INHIBITORS AND PRO-APOPTOTIC AGENTS FOR TREATING CANCER | Les Laboratoires Servier (FR) | 2022-06-01 | — | — | EP | claimed |
| EP-4003988-A1 | 3,6-DIAMINO-PYRIDAZIN-3-YL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS PRO-APOPTOTIC AGENTS | Les Laboratoires Servier (FR) | 2022-06-01 | — | — | EP | claimed |
| CN-114450284-A | 6, 7-dihydro-5H-pyrido [2,3-C ] pyridazine derivatives and related compounds as BCL-XL protein inhibitors and pro-apoptotic agents for the treatment of cancer | 法国施维雅药厂 | 2022-05-06 | — | — | CN | claimed |
| EP-3952995-A1 | BICYCLIC HETEROARYL DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS | Riboscience LLC (US) | 2022-02-16 | — | — | EP | claimed |
| EP-0049814-B1 | CEPHALOSPORIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1985-01-09 | — | — | EP | claimed |
| EP-0006227-B1 | ANTITHROMBOTIC PHARMACEUTICAL PREPARATION CONTAINING 2,2'-DITHIOBIS BENZAMIDE DERIVATIVES AND NEW 2,2'-DITHIOBIS BENZAMIDE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD (JP) | 1984-12-27 | — | — | EP | claimed |
| US-4452789-A | CARDIOVASCULAR DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 1984-06-05 | — | — | US | claimed |
| EP-0021176-B1 | CEPHALOSPORIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1984-01-18 | — | — | EP | claimed |
| US-4362725-A | ANTIBIOTICS | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-12-07 | — | — | US | claimed |
| EP-0060439-A2 | Spinning mass containing an optical bleaching agent for the preparation of regenerated cellulose fibres | BAYER AG (DE) | 1982-09-22 | — | — | EP | claimed |
| EP-0049814-A2 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | Dr. Karl Thomae GmbH (DE) | 1982-04-21 | — | — | EP | claimed |
| US-4315938-A | ANTIDEPRESSANTS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-02-16 | — | — | US | claimed |
| EP-0044992-A1 | Lactams, process for their preparation and pharmaceutical compositions containing them | Dr. Karl Thomae GmbH (DE) | 1982-02-03 | — | — | EP | claimed |
| US-4276297-A | ANTIULCER AGENTS | PFIZER INC. (US) | 1981-06-30 | — | — | US | claimed |