Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 3/20 | 0.69 |
| ▸ | AURKA | O14965 | 2/20 | 0.69 |
| ▸ | KDR | P35968 | 15/20 | 0.65 |
| ▸ | RET | P07949 | 3/20 | 0.65 |
| ▸ | KIF5B | P33176 | 2/20 | 0.65 |
| ▸ | EGFR | P00533 | 5/20 | 0.65 |
| ▸ | GAK | O14976 | 1/20 | 0.65 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.65 |
| ▸ | STK10 | O94804 | 1/20 | 0.65 |
| ▸ | FLT3 | P36888 | 1/20 | 0.65 |
| ▸ | JAK3 | P52333 | 1/20 | 0.65 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.65 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.65 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.65 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.65 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.65 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.65 |
| ▸ | LCK | P06239 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689820 | 0.96 | AURKB (0.73) | AURKBAURKAKDRRETKIF5B | |
| SCHEMBL5473733 | 0.92 | KDR (0.74) | AURKBAURKAKDRRETEGFR | |
| Hydrochloric Acid SCHEMBL5477767 | 0.91 | EGFR (0.73) | AURKBAURKAKDRRETEGFR | |
| SCHEMBL3239025 | 0.88 | EGFR (0.66) | AURKBAURKAKDRRETKIF5B | |
| SCHEMBL6688859 | 0.86 | KDR (0.67) | AURKBAURKAKDRRETEGFR | |
| SCHEMBL5242610 | 0.84 | KDR (0.81) | AURKBAURKAKDRRETKIF5B | |
| SCHEMBL14964757 | 0.84 | EGFR (0.81) | KDRRETKIF5BEGFRGAK | |
| SCHEMBL5239599 | 0.84 | EGFR (0.80) | AURKBAURKAKDRRETKIF5B | |
| SCHEMBL3527282 | 0.84 | AURKB (0.94) | AURKBAURKAKDREGFRIRAK4 | |
| Hydrochloric Acid SCHEMBL3531894 | 0.83 | AURKB (0.92) | AURKBAURKAKDREGFRIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069145-A2 | ANTICANCER COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2004-08-19 | — | — | WO | disclosed |