Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.43 |
| ▸ | RARG | P13631 | 3/20 | 0.43 |
| ▸ | IKBKB | O14920 | 4/20 | 0.42 |
| ▸ | RARA | P10276 | 3/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6134072 | 0.90 | SIRT2 (0.39) | RARBRARGRARA | |
| SCHEMBL6134106 | 0.88 | ACVRL1 (0.34) | — | |
| SCHEMBL6689980 | 0.88 | CSNK2A2 (0.46) | RARBRARGCSNK2A1CSNK2A2CHEK1 | |
| SCHEMBL6134935 | 0.86 | ALDH1A1 (0.34) | SMN1; SMN2 | |
| SCHEMBL6134891 | 0.84 | USP2 (0.46) | SMN1; SMN2 | |
| SCHEMBL6134410 | 0.79 | ALDH1A1 (0.41) | CSNK2A1CSNK2A2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6134391 | 0.75 | CHKA (0.36) | RAB9ASMN1; SMN2 | |
| SCHEMBL2942401 | 0.73 | USP2 (0.50) | CHEK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6134369 | 0.73 | HDAC3 (0.46) | RAB9ASMN1; SMN2 | |
| SCHEMBL7396944 | 0.73 | RARB (0.66) | RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004113368-A1 | CYCLIC LIPOPEPTIDES | ASTELLAS PHARMA INC. (JP) | 2004-12-29 | — | — | WO | disclosed |