Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6688972 | 1.00 | MAPT (0.40) | MAPTCACNA1BAPBA1ALDH1A1KMT2A | |
| SCHEMBL11223609 | 0.79 | MAPT (0.41) | MAPTCACNA1BAPBA1ALDH1A1KMT2A | |
| SCHEMBL11388692 | 0.77 | MAPT (0.40) | MAPTCACNA1BAPBA1ALDH1A1KMT2A | |
| SCHEMBL6282256 | 0.73 | ALDH1A1 (0.42) | MAPTALDH1A1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL6282254 | 0.73 | ALDH1A1 (0.42) | MAPTALDH1A1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL9503508 | 0.71 | TSHR (0.43) | MAPTCACNA1BAPBA1ALDH1A1KMT2A | |
| SCHEMBL19031254 | 0.69 | ALDH1A1 (0.36) | MAPTCACNA1BAPBA1ALDH1A1KMT2A | |
| SCHEMBL11727940 | 0.69 | MAPT (0.36) | MAPTCACNA1BAPBA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6284069 | 0.68 | ALDH1A1 (0.43) | MAPTALDH1A1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL6284064 | 0.68 | ALDH1A1 (0.43) | MAPTALDH1A1KMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286981-B1 | METHOD FOR THE PRODUCTION OF 2- COUMARONE AND SUBSTITUTED 2-COUMARONES | DSM FINE CHEM AUSTRIA GMBH (AT) | 2004-08-04 | — | — | EP | claimed |