SCHEMBL6689158

SCHEMBL6689158

CC(=O)Nc1ccccc1NC(C)=O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.74
HPGD P15428 1/20 0.74
MAPK1 P28482 1/20 0.67
SMN1; SMN2 Q16637 5/20 0.64
TSHR P16473 3/20 0.64
HTT P42858 1/20 0.64
CYP2C19 P33261 2/20 0.63
POLB P06746 1/20 0.63
NAPRT Q6XQN6 1/20 0.61
HSD17B10 Q99714 1/20 0.61
RECQL P46063 1/20 0.58
KMT2A Q03164 2/20 0.58
MEN1 O00255 1/20 0.58
MAOA P21397 1/20 0.57
LMNA P02545 1/20 0.56
RXFP1 Q9HBX9 1/20 0.55
CYP1A2 P05177 1/20 0.55
CYP3A4 P08684 1/20 0.55
CYP2D6 P10635 1/20 0.55
CYP2C9 P11712 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14044502 0.91 ALDH1A1 (0.63) ALDH1A1HPGDMAPK1SMN1; SMN2TSHR
SCHEMBL10461228 0.89 ALDH1A1 (0.61) ALDH1A1HPGDMAPK1SMN1; SMN2TSHR
SCHEMBL3412160 0.89 ALDH1A1 (0.61) ALDH1A1HPGDMAPK1SMN1; SMN2TSHR
SCHEMBL10605873 0.89 ALDH1A1 (0.61) ALDH1A1HPGDMAPK1SMN1; SMN2TSHR
SCHEMBL6326388 0.87 ALDH1A1 (0.65) ALDH1A1HPGDMAPK1SMN1; SMN2TSHR
SCHEMBL25077974 0.87 ALDH1A1 (0.59) ALDH1A1HPGDMAPK1SMN1; SMN2TSHR
SCHEMBL3363637 0.87 ALDH1A1 (0.59) ALDH1A1HPGDMAPK1SMN1; SMN2TSHR
SCHEMBL9153331 0.87 ALDH1A1 (0.59) ALDH1A1HPGDMAPK1SMN1; SMN2TSHR
SCHEMBL6855902 0.87 ALDH1A1 (0.59) ALDH1A1HPGDMAPK1SMN1; SMN2TSHR
SCHEMBL728079 0.85 ALDH1A1 (0.63) ALDH1A1HPGDMAPK1SMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5025107-A Process for coproduction of arylene diamine dihalides and alkyl halides EASTMAN KODAK COMPANY (US) 1991-06-18 US claimed
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 US disclosed
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 US disclosed
US-10184052-B2 Near infrared radiation-absorbing composition, near infrared radiation cut-off filter and production method therefor, and camera module and production method therefor FUJIFILM CORPORATION (JP) 2019-01-22 US disclosed
US-20180094086-A1 NEAR INFRARED ABSORBING COMPOSITION, NEAR INFRARED CUT FILTER, METHOD OF MANUFACTURING NEAR INFRARED CUT FILTER, DEVICE, METHOD OF MANUFACTURING COPPER-CONTAINING POLYMER, AND COPPER-CONTAINING POLYMER FUJIFILM CORPORATION (JP) 2018-04-05 US disclosed
US-20180094086-A1 NEAR INFRARED ABSORBING COMPOSITION, NEAR INFRARED CUT FILTER, METHOD OF MANUFACTURING NEAR INFRARED CUT FILTER, DEVICE, METHOD OF MANUFACTURING COPPER-CONTAINING POLYMER, AND COPPER-CONTAINING POLYMER FUJIFILM CORPORATION (JP) 2018-04-05 US disclosed
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-20160304730-A1 NEAR INFRARED RADIATION-ABSORBING COMPOSITION, NEAR INFRARED RADIATION CUT-OFF FILTER AND PRODUCTION METHOD THEREFOR, AND CAMERA MODULE AND PRODUCTION METHOD THEREFOR FUJIFILM CORPORATION (JP) 2016-10-20 US disclosed
US-20160304730-A1 NEAR INFRARED RADIATION-ABSORBING COMPOSITION, NEAR INFRARED RADIATION CUT-OFF FILTER AND PRODUCTION METHOD THEREFOR, AND CAMERA MODULE AND PRODUCTION METHOD THEREFOR FUJIFILM CORPORATION (JP) 2016-10-20 US disclosed
EP-0950669-B1 Method of catalytic crosslinking of polymers and two-pack composition used therein ROHM & HAAS (US) 2004-09-08 EP disclosed
US-6306991-B1 TWO PART COATING COMPOSITION WITH TWO CONTAINERS, OXIDATIVE POLYMERS WITH CROSSLINKABLE FUNCTIONAL GROUPS ROHM AND HAAS COMPANY 2001-10-23 US disclosed
US-6149977-A CONTACTING THE OXIDATIVE POLYMER WITH A CATALYTIC AMOUNT OF AN OXIDIZING ENZYME, SUCH AS HORSERADISH PEROXIDASE. ROHM AND HAAS COMPANY (US) 2000-11-21 US disclosed
EP-0950669-A2 Method of catalytic crosslinking of polymers and two-pack composition used therein ROHM AND HAAS COMPANY (US) 1999-10-20 EP disclosed
US-5025107-A Process for coproduction of arylene diamine dihalides and alkyl halides EASTMAN KODAK COMPANY (US) 1991-06-18 US disclosed
US-4600797-A NITRATING AN AMINOBENZENE WHICH HAS A PROTECTEDD AMINO GROUP BAYER AKTIENGESELLSCHAFT (DE) 1986-07-15 US disclosed
EP-0049711-B1 PROCESS FOR THE PRODUCTION OF NITRO-AMINO-BENZENES BAYER AG (DE) 1984-02-29 EP disclosed
EP-0049711-A1 Process for the production of nitro-amino-benzenes BAYER AG (DE) 1982-04-21 EP disclosed
US-4029609-A HEAT RESISTANCE TOYO BOSEKI KABUSHIKI KAISHA (JA) 1977-06-14 US disclosed
US-3989840-A Control of animal parasites with ring-substituted N-(2,2-difluoroalkanoyl)-O-phenylenediamines ELI LILLY AND COMPANY (US) 1976-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE C9, SET, CRY1 ALDH1A1 2313/4885HPGD 4594/4885MAPK1 4684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.