Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 6/20 | 0.42 |
| ▸ | RXRA | P19793 | 3/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | F9 | P00740 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6783789 | 0.85 | KLKB1 (0.48) | KLKB1MAPK14F10RXRANR1H2 | |
| SCHEMBL6712376 | 0.82 | MAPK14 (0.45) | KLKB1MAPK14F10RXRANR1H2 | |
| SCHEMBL2259914 | 0.79 | NPY5R (0.52) | KLKB1F10RXRANR1H2NR1H3 | |
| SCHEMBL12361685 | 0.78 | F10 (0.49) | KLKB1F10F2 | |
| SCHEMBL2258704 | 0.78 | NPY5R (0.54) | KLKB1F10NPY5RMAPTSMN1; SMN2 | |
| SCHEMBL2260222 | 0.77 | NPY5R (0.53) | KLKB1F10NPY5RF2 | |
| SCHEMBL12361694 | 0.77 | F10 (0.47) | KLKB1MAPK14F10F2KMT2A | |
| SCHEMBL2259628 | 0.77 | KDR (0.54) | KLKB1F10MAPTSMN1; SMN2KMT2A | |
| SCHEMBL2257037 | 0.76 | ALDH1A1 (0.46) | KLKB1F10MAPTF2 | |
| SCHEMBL2257668 | 0.76 | IGF1R (0.53) | F10MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427705-A2 | INSECTICIDAL DIAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003026415-A2 | INSECTICIDAL DIAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-04-03 | — | — | WO | disclosed |