Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK4 | O00444 | 3/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.76 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.72 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.72 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.72 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.72 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.72 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.72 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.72 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.70 |
| ▸ | RET | P07949 | 2/20 | 0.67 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.67 |
| ▸ | PLK1 | P53350 | 2/20 | 0.67 |
| ▸ | FLT3 | P36888 | 1/20 | 0.67 |
| ▸ | APP | P05067 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | SNCA | P37840 | 1/20 | 0.64 |
| ▸ | GSK3B | P49841 | 5/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6857929 | 0.87 | MEN1 (0.73) | PLK4MEN1KMT2ALRRK2MAP1LC3B | |
| SCHEMBL6835454 | 0.87 | MEN1 (0.73) | PLK4MEN1KMT2ALRRK2MAP1LC3B | |
| SCHEMBL29736859 | 0.86 | PLK4 (0.71) | PLK4MEN1KMT2APSEN1PSEN2 | |
| SCHEMBL3754416 | 0.86 | MAP1LC3B (0.88) | PLK4MEN1KMT2APSEN1PSEN2 | |
| SCHEMBL5774043 | 0.86 | MAP1LC3B (0.88) | PLK4MEN1KMT2APSEN1PSEN2 | |
| SCHEMBL5774039 | 0.86 | MAP1LC3B (0.88) | PLK4MEN1KMT2APSEN1PSEN2 | |
| SCHEMBL3750013 | 0.85 | MAP1LC3B (0.69) | PLK4MEN1KMT2APSEN1PSEN2 | |
| SCHEMBL5727968 | 0.84 | MEN1 (0.66) | PLK4MEN1KMT2APSEN1PSEN2 | |
| SCHEMBL5727972 | 0.84 | MEN1 (0.66) | PLK4MEN1KMT2APSEN1PSEN2 | |
| SCHEMBL5370064 | 0.84 | PSEN1 (0.71) | PLK4MEN1KMT2APSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069998-A2 | OXINDOLE DERIVATIVES AS ANTIMICROBIAL AGENTS | ARROW THERAPEUTICS LIMITED (GB) | 2004-08-19 | — | — | WO | disclosed |