Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 4/20 | 0.67 |
| ▸ | EGFR | P00533 | 2/20 | 0.67 |
| ▸ | IGF1R | P08069 | 1/20 | 0.67 |
| ▸ | CTRC | Q99895 | 1/20 | 0.61 |
| ▸ | RAF1 | P04049 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | EEF2K | O00418 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318426 | 0.87 | ERBB2 (0.68) | ERBB2EGFRIGF1RCTRCSIRT1 | |
| SCHEMBL7318433 | 0.87 | ERBB2 (0.68) | ERBB2EGFRIGF1RCTRCSIRT1 | |
| SCHEMBL6685283 | 0.85 | RAF1 (0.69) | EGFRRAF1SIRT1SIRT2SIRT3 | |
| SCHEMBL5363945 | 0.84 | ERBB2 (0.58) | ERBB2EGFRIGF1RCTRCSIRT1 | |
| SCHEMBL6686685 | 0.84 | RAF1 (0.54) | ERBB2EGFRIGF1RRAF1SIRT1 | |
| SCHEMBL6697120 | 0.84 | RAF1 (0.54) | ERBB2EGFRIGF1RRAF1SIRT1 | |
| SCHEMBL7310707 | 0.84 | ERBB2 (0.64) | ERBB2EGFRIGF1RCTRCRAF1 | |
| SCHEMBL7310712 | 0.84 | ERBB2 (0.64) | ERBB2EGFRIGF1RCTRCRAF1 | |
| SCHEMBL1394682 | 0.81 | SIRT1 (0.62) | EGFRRAF1SIRT1SIRT2SIRT3 | |
| SCHEMBL1394680 | 0.81 | SIRT1 (0.62) | EGFRRAF1SIRT1SIRT2SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069998-A2 | OXINDOLE DERIVATIVES AS ANTIMICROBIAL AGENTS | ARROW THERAPEUTICS LIMITED (GB) | 2004-08-19 | — | — | WO | disclosed |