SCHEMBL6689571

SCHEMBL6689571

COC(=O)NC1(S(=O)(=O)O)N=c2ccccc2=N1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.35
ALDH1A1 P00352 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 4/20 0.34
MEN1 O00255 3/20 0.34
HPGD P15428 2/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
POLB P06746 1/20 0.32
KDM4E B2RXH2 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
CA9 Q16790 2/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA5A P35218 1/20 0.32
TSHR P16473 1/20 0.32
GAA P10253 2/20 0.31
HTT P42858 2/20 0.31
STAT3 P40763 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4364129 0.76 HPGD (0.36) LMNAALDH1A1SMN1; SMN2KMT2AMEN1
SCHEMBL11774564 0.71 EPHX2 (0.31)
SCHEMBL11739823 0.69 FNTA (0.39) LMNAALDH1A1SMN1; SMN2HPGDHSD17B10
SCHEMBL28827975 0.68 MAPT (0.42) LMNAALDH1A1SMN1; SMN2MAPTKMT2A
SCHEMBL3670914 0.64 HTT (0.43) ALDH1A1SMN1; SMN2HPGDPOLBTSHR
SCHEMBL149345 0.64 TSHR (0.34) LMNAALDH1A1SMN1; SMN2MAPTHPGD
SCHEMBL989262 0.64 TSHR (0.34) LMNAALDH1A1SMN1; SMN2MAPTHSD17B10
SCHEMBL6519735 0.63 TSHR (0.31) LMNAALDH1A1SMN1; SMN2MAPTKDM4E
SCHEMBL5204065 0.61 KMT2A (0.36) ALDH1A1SMN1; SMN2KMT2AMEN1L3MBTL1
SCHEMBL83480 0.61 TSHR (0.37) LMNAALDH1A1SMN1; SMN2KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2004231894-A AQUEOUS INK COMPOSITION MITSUBISHI PENCIL CO LTD 2004-08-19 JP disclosed